Recombinant Thyroid Stimulating Hormone Receptor (TSHR)

• Catalog number
  RPC825Hu01-10ug
• Price
  Please ask
• Size
  10ug

• Description
  Recombinant Human Thyroid Stimulating Hormone Receptor expressed in: E.coli
• Specifications
  Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Gly21~Gly413; Purity: > 95%; Endotoxin level:
• Additional_information
  Uniprot ID: Inquire; Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 48.3kDa; Isoelectric Point: 5.4
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Additional description
  Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Thyroid   Stimulating   Hormone   Receptor   TSHR  
• Gene symbol
  TSHR
• Short name
  Recombinant Thyroid Stimulating Hormone Receptor (TSHR)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Rec. Thyroid Stimulating Hormone Receptor (TSHR)
• Alternative technique
  rec
• Tissue
  thyroid

Gene info

• Identity
  HGNC:12373
• Gene
  TSHR
• Long gene name
  thyroid stimulating hormone receptor
• Synonyms
  • LGR3
• GenBank acession
  • AY429111
• Locus
  14q24-q31
• Discovery year
  1990-03-05
• Entrez gene record
  7253
• Pubmed identfication
  • 2558651
  • 2610690
• RefSeq identity
  • NM_000369
• Classification
  • Glycoprotein hormone receptors
• VEGA ID
  OTTHUMG00000171429
• Locus Specific Databases
  • TSH Receptor mutation database
  • LRG_523

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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