Recombinant Signal Transducer And Activator Of Transcription 3 (STAT3)

• Catalog number
  RPB743Mi02
• Price
  Please ask
• Size
  300

• Source
  Prokaryotic expression
• Predicted Molecular Mass KD
  13.2kDa
• Accurate Molecular Mass KD
  NA
• Organism species
  Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Bos taurus; Bovine (Cattle)
• Item Name
  Signal Transducer And Activator Of Transcription 3
• Alternative Names
  APRF; Acute-Phase Response Factor
• Research Area
  Signal transduction;Apoptosis;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Purity
  ≥ 95%
• Protein length
  Ile576~Pro678
• Tag
  N-terminal His-Tag
• Expression System
  Prokaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Manual link
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants
• Description
  The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  Signal   Transducer   Activator   Transcription   STAT3  
• Gene symbol
  STAT3
• Short name
  Recombinant Signal Transducer Activator Of Transcription 3 (STAT3)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E.coli
• Species
  Multi-species
• Alternative name
  Rec. Signal Transducer And Activator on Transcription 3 (signal transducer and activator on transcription 3 (acute-phase response factor))
• Alternative technique
  rec
• Alternative to gene target
  signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541

Gene info

• Identity
  HGNC:11364
• Gene
  STAT3
• Long gene name
  signal transducer and activator of transcription 3
• Synonyms gene name
  • signal transducer and activator of transcription 3 (acute-phase response factor)
• Synonyms
  • APRF
• GenBank acession
  • BC014482
• Locus
  17q21.2
• Discovery year
  1995-11-08
• Entrez gene record
  6774
• Pubmed identfication
  • 7512451
• RefSeq identity
  • NM_139276
  • NM_003150
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000150645
• Locus Specific Databases
  • STAT3base: Mutation registry for Hyper-IgE syndrome
  • LRG_112

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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