Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb)
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Catalog number
RPC061Mu01
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Price
Please ask
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Size
10ug
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Source
Prokaryotic expression
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Predicted Molecular Mass KD
32.0kDa
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Accurate Molecular Mass KD
38kDa
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Organism species
Mus musculus (Mouse)
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Item Name
Platelet Derived Growth Factor Receptor Beta
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Alternative Names
CD140b; JTK12; PDGF-R-Beta; PDGFR; PDGFR1; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; Beta-type platelet-derived growth factor receptor
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Research Area
Signal transduction;Tumor immunity;Infection immunity;Hematology;
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Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
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Traits
Freeze-dried powder
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Isoelectric Point
6.5
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Purity
≥ 98%
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Protein length
Val337~Pro583
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Tag
two N-terminal Tags, His-tag and T7-tag
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Expression System
Prokaryotic expression
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Application
Positive Control; Immunogen; SDS-PAGE; WB.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
PDGFRB
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Short name
Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E.coli
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Species
Mus musculus (Mouse)
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Alternative name
Rec. Platelet Derived Growth Factor Receptor b (platelet-derived growth factor receptor, b polypeptide)
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Alternative technique
rec
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Alternative to gene target
platelet-derived growth factor receptor, beta polypeptide, CD140B and IBGC4 and IMF1 and JTK12 and PDGFR and PDGFR-1 and PDGFR1, PDGFRB and IDBG-53326 and ENSG00000113721 and 5159, transferase activity, nuclei, Pdgfrb and IDBG-150834 and ENSMUSG00000024620 and 18596, BT.74208 and IDBG-646273 and ENSBTAG00000002804 and 527165
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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