Recombinant Immunoglobulin E (IgE)

• Catalog number
  RPA545Po01-200ug
• Price
  Please ask
• Size
  200ug

• Description
  Recombinant Pig Immunoglobulin E expressed in: E.coli
• Specifications
  Host species: Sus scrofa; Porcine (Pig); Expression system: E.coli; Expression region: Ser1~Lys424; Purity: > 95%; Endotoxin level:
• Additional_information
  Uniprot ID: Inquire; Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 50.5kDa; Isoelectric Point: 7.9
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Properties
  Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Immunoglobulin  
• Gene symbol
  IGHV1-69
• Short name
  Recombinant Immunoglobulin E (IgE)
• Technique
  Recombinant, IgE, IgEs, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Isotype
  IgE, IgE
• Alternative name
  Rec. Immunoglobulin E (immunoglobuline E)
• Alternative technique
  rec, immunoglobulin-e

Gene info

• Identity
  HGNC:5558
• Gene
  IGHV1-69
• Long gene name
  immunoglobulin heavy variable 1-69
• Synonyms gene
  • IGHV1-E
• GenBank acession
  • L22582
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28461
• Pubmed identfication
  • 8469934
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151862

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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