Recombinant Hypoxia Inducible Factor 1 Alpha Subunit Inhibitor (HIF1aN)

• Catalog number
  RPG323Hu01-200ug
• Price
  Please ask
• Size
  200ug

• Description
  Recombinant Human Hypoxia Inducible Factor 1 Alpha Subunit Inhibitor expressed in: E.coli
• Specifications
  Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Ala2~Asn349; Purity: ≥ 92%; Endotoxin level:
• Additional_information
  Uniprot ID: Q9NWT6; Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 43.9kDa; Isoelectric Point: Inquire
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Additional description
  The Recombinant Hypoxia Factor 1 Alpha Subunit Inhibitor (HIF1aN) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Hypoxia   Factor   Alpha   Subunit   Inhibitor   HIF1aN  
• Gene symbol
  HIF1AN
• Short name
  Recombinant Hypoxia Factor 1 Alpha Subunit Inhibitor (HIF1aN)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Rec. Hypoxia Inducible Factor 1 a functionnal sequence suppressor (HIF1aN)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:17113
• Gene
  HIF1AN
• Long gene name
  hypoxia inducible factor 1 subunit alpha inhibitor
• Synonyms
  • FLJ20615
  • DKFZp762F1811
  • FLJ22027
  • FIH1
• Synonyms name
  • Peptide-aspartate beta-dioxygenase
• GenBank acession
  • AK000622
• Locus
  10q24.31
• Discovery year
  2001-11-27
• Entrez gene record
  55662
• Pubmed identfication
  • 11641274
• RefSeq identity
  • NM_017902
• Classification
  • JmjC hydroxylases
• VEGA ID
  OTTHUMG00000018911

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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