Recombinant Glutamate Cysteine Ligase, Modifier Subunit (GCLM)

• Catalog number
  RPB038Hu01-1MG
• Price
  Please ask
• Size
  1MG

• Description
  Recombinant Human Glutamate Cysteine Ligase, Modifier Subunit expressed in: E.coli
• Specifications
  Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Ser40~Ser251; Purity: ≥ 95%; Endotoxin level:
• Additional_information
  Uniprot ID: P48507; Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 27.7kDa; Isoelectric Point: 4.9
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Gene
  Cys or cysteines ChEMBL54943
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Glutamate   Cysteine   Ligase   Modifier   Subunit   GCLM  
• Gene symbol
  GCLM
• Short name
  Recombinant Glutamate Cysteine Ligase, Modifier Subunit (GCLM)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Rec. Glutamate Cysteine Ligase, Modifier functionnal sequence (glutamate-cysteine ligase, modifier subunit)
• Alternative technique
  rec
• Alternative to gene target
  glutamate-cysteine ligase, modifier subunit, GLCLR, GCLM and IDBG-100355 and ENSG00000023909 and 2730, protein heterodimerization activity, Cytoplasm, Gclm and IDBG-191550 and ENSMUSG00000028124 and 14630, GCLM and IDBG-636430 and ENSBTAG00000007842 and 525659

Gene info

• Identity
  HGNC:4312
• Gene
  GCLM
• Long gene name
  glutamate-cysteine ligase modifier subunit
• Synonyms gene
  • GLCLR
• Synonyms gene name
  • glutamate-cysteine ligase, modifier subunit
• Synonyms name
  • gamma-glutamylcysteine synthetase
• GenBank acession
  • L35546
• Locus
  1p22.1
• Discovery year
  1995-01-30
• Entrez gene record
  2730
• Pubmed identfication
  • 7826375
• RefSeq identity
  • NM_002061
• VEGA ID
  OTTHUMG00000010562

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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