Recombinant Duffy Blood Group Chemokine Receptor (DARC)

• Catalog number
  RPB683Mu01
• Price
  Please ask
• Size
  450

• Source
  Prokaryotic expression
• Predicted Molecular Mass KD
  60.4kDa
• Accurate Molecular Mass KD
  NA
• Organism species
  Mus musculus (Mouse)
• Item Name
  Duffy Blood Group Chemokine Receptor
• Alternative Names
  CD234; CCBP1; Dfy; FY; GPD; Duffy Antigen; Ackr1
• Research Area
  Signal transduction;Hematology;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Isoelectric Point
  7.3
• Purity
  ≥ 92%
• Protein length
  Met71~Leu330
• Tag
  two N-terminal Tags, His-tag and GST-tag
• Expression System
  Prokaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Manual link
• Description
  Blood is slightly basic and contains proteins, hemoglobin, albumins in its serum. Cloud Clone Corp supplies this blood related product in 1. Chemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by Cloud Clone Corp in 1. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Duffy   Group   Chemokine   Receptor   DARC  
• Gene symbol
  ACKR1
• Short name
  Recombinant Duffy Blood Group Chemokine Receptor (DARC)
• Technique
  Recombinant, blood, blood samples, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E.coli
• Species
  Mus musculus (Mouse)
• Alternative name
  Rec. Duffy Blood family Chemokine Receptor (Duffy blood group, chemokine receptor)
• Alternative technique
  rec, sera
• Alternative to gene target
  Duffy blood group, chemokine receptor, CCBP1 and CD234 and DARC and Dfy and FY and GPD and GpFy and WBCQ1, DARC and IDBG-246055 and ENSG00000213088 and 2532, C-C chemokine binding, Plasma membranes, Darc and IDBG-205828 and ENSMUSG00000037872 and 13349, BT.27077 and IDBG-630777 and ENSBTAG00000003220 and 528076
• Tissue
  blood

Gene info

• Identity
  HGNC:4035
• Gene
  ACKR1
• Long gene name
  atypical chemokine receptor 1 (Duffy blood group)
• Synonyms gene
  • FY
  • DARC
• Synonyms gene name
  • Duffy blood group
  • Duffy blood group, chemokine receptor
  • Duffy blood group, atypical chemokine receptor
• Synonyms
  • CCBP1
  • GPD
  • Dfy
  • CD234
• Synonyms name
  • atypical chemokine receptor 1
  • glycoprotein D
• GenBank acession
  • U01839
• Locus
  1q23.2
• Discovery year
  2001-06-22
• Entrez gene record
  2532
• Pubmed identfication
  • 8248172
  • 7663520
  • 16148
• RefSeq identity
  • NM_002036
• Classification
  • Atypical chemokine receptors
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000037182
• Locus Specific Databases
  • LRG_801

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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