Recombinant Constitutive Androstane Receptor (CAR)

• Catalog number
  RPC422Ra01
• Price
  Please ask
• Size
  390

• Source
  Prokaryotic expression
• Predicted Molecular Mass KD
  31.8kDa
• Accurate Molecular Mass KD
  NA
• Organism species
  Rattus norvegicus (Rat)
• Item Name
  Constitutive Androstane Receptor
• Alternative Names
  NR1I3; NR1-I3; CAR1; MB67; Nuclear Receptor Subfamily 1,Group I,Member 3; Constitutive active response; Constitutive activator of retinoid response; Orphan nuclear receptor MB67
• Research Area
  Signal transduction;Metabolic pathway;Endocrinology;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Purity
  > 90%
• Protein length
  Met1~Glu247
• Tag
  two N-terminal Tags, His-tag and T7-tag
• Expression System
  Prokaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Manual link
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Constitutive   Androstane   Receptor   CAR  
• Gene symbol
  CXADR, CXADRP1, NR1I3, SPG7
• Short name
  Recombinant Constitutive Androstane Receptor (CAR)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E.coli
• Species
  Rattus norvegicus (Rat)
• Alternative name
  Rec. Constitutive Androstane Receptor (CAR)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:2559
• Gene
  CXADR
• Long gene name
  CXADR Ig-like cell adhesion molecule
• Synonyms gene name
  • coxsackie virus and adenovirus receptor
  • CXADR, Ig-like cell adhesion molecule
• Synonyms
  • CAR
• GenBank acession
  • Y07593
• Locus
  21q21.1
• Discovery year
  1998-03-24
• Entrez gene record
  1525
• Pubmed identfication
  • 9036860
  • 9096397
  • 20813955
• Classification
  • IgCAM CXADR-related subfamily
  • V-set domain containing
• VEGA ID
  OTTHUMG00000074508

Gene info

• Identity
  HGNC:23770
• Gene
  CXADRP1
• Long gene name
  CXADR pseudogene 1
• Synonyms gene name
  • coxsackie virus and adenovirus receptor pseudogene 1
• Synonyms
  • CAR
  • CXADRP
• Locus
  21q11.2
• Discovery year
  2008-01-31
• Entrez gene record
  653108
• VEGA ID
  OTTHUMG00000074204

Gene info

• Identity
  HGNC:7969
• Gene
  NR1I3
• Long gene name
  nuclear receptor subfamily 1 group I member 3
• Synonyms gene name
  • nuclear receptor subfamily 1, group I, member 3
• Synonyms
  • MB67
  • CAR1
  • CAR
• Synonyms name
  • constitutive androstane receptor
• GenBank acession
  • Z30425
• Locus
  1q23.3
• Discovery year
  1999-09-23
• Pubmed identfication
  • 8114692
• Classification
  • Nuclear receptor subfamily 1 group I
• VEGA ID
  OTTHUMG00000034347

Gene info

• Identity
  HGNC:11237
• Gene
  SPG7
• Long gene name
  SPG7 matrix AAA peptidase subunit, paraplegin
• Synonyms gene
  • CMAR
• Synonyms gene name
  • cell matrix adhesion regulator
  • spastic paraplegia 7 (pure and complicated autosomal recessive)
• Synonyms
  • CAR
  • SPG5C
• Synonyms name
  • paraplegin
• GenBank acession
  • Y16610
• Locus
  16q24.3
• Discovery year
  1998-06-25
• Entrez gene record
  6687
• Pubmed identfication
  • 9635427
  • 9634528
• RefSeq identity
  • NM_003119
• Classification
  • AAA ATPases
• VEGA ID
  OTTHUMG00000138046
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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