Recombinant Cancerous Inhibitor Of PP2A (CIP2A)

Source

Prokaryotic expression
Predicted Molecular Mass KD

69.2kDa
Accurate Molecular Mass KD

NA
Organism species

Homo sapiens (Human)
Item Name

Cancerous Inhibitor Of PP2A
Alternative Names

p90; KIAA1524
Research Area

Tumor immunity;
Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Traits

Freeze-dried powder
Isoelectric Point

5.9
Purity

≥ 75%
Protein length

Asn230~Glu560
Tag

two N-terminal Tags, His-tag and GST-tag
Expression System

Prokaryotic expression
Application

Positive Control; Immunogen; SDS-PAGE; WB.
Manual link
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

Cancerous Inhibitor PP2A CIP2A
Gene symbol

CIP2A, LINC00665, PPP2R1B, PPP2R1A
Short name

Recombinant Cancerous Inhibitor Of PP2A (CIP2A)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E.coli
Species

Homo sapiens (Human)
Alternative name

Rec. Cancerous suppressor on PP2A (CIP2A)
Alternative technique

rec

Identity

HGNC:29302
Gene

CIP2A
Long gene name

cellular inhibitor of PP2A
Synonyms gene
- KIAA1524
Synonyms gene name
- KIAA1524
- cell proliferation regulating inhibitor of protein phosphatase 2A
Synonyms name
- cancerous inhibitor of protein phosphatase 2A
GenBank acession
- AB040957
Locus

3q13.13
Discovery year

2005-01-24
Entrez gene record

57650
Pubmed identfication
RefSeq identity
- NM_020890
Classification
- Armadillo like helical domain containing
VEGA ID

OTTHUMG00000159233

Identity

HGNC:9303
Gene

PPP2R1B
Long gene name

protein phosphatase 2 scaffold subunit Abeta
Synonyms gene name
- protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
- protein phosphatase 2 regulatory subunit A, beta
Synonyms
- PR65B
- PP2A-Abeta
Synonyms name
- PP2A-A-beta
- protein phosphatase 2A, regulatory subunit A, beta isoform
GenBank acession
- AF087438
Locus

11q23.1
Discovery year

1993-01-25
Entrez gene record

5519
Pubmed identfication
- 2159327
- 9795170
RefSeq identity
- NM_002716
Classification
- STRIPAK complex
- Protein phosphatase 2 scaffold subunits
- Armadillo like helical domain containing
VEGA ID

OTTHUMG00000166741

Identity

HGNC:9302
Gene

PPP2R1A
Long gene name

protein phosphatase 2 scaffold subunit Aalpha
Synonyms gene name
- protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
Synonyms
- PR65A
- PP2A-Aalpha
- PP2AA
Synonyms name
Locus

19q13.41
Discovery year

1993-01-25
Entrez gene record

5518
RefSeq identity
- NM_014225
Classification
- STRIPAK complex
- Protein phosphatase 2 scaffold subunits
- Armadillo like helical domain containing
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000137367

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data