Rabbit polyclonal-Anti-Breast Cancer Susceptibility Protein 1 (BRCA1)-20ug

#

• Catalog number
  PAB376Ra01-20ug
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• Size
  20ug

# #

• Organism Species
  Rattus norvegicus (Rat)
• Source
  Polyclonal antibody preparation
• Purification
  Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Buffer Formulation
  PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Item Name
  Breast Cancer Susceptibility Protein 1
• Immunogen
  RPB376Ra01-Recombinant Breast Cancer Susceptibility Protein 1 (BRCA1)
• Image number
  2
• Species reactivity
  Rat
• Sequence of immunogen
  BRCA1 (Ser1579~Glu1811)
• Aplication
  WB,IHC
• Clonality
  Rabbit polyclonal
• Concentration
  500ug/ml
• Alternative Names
  BRCAI; BRCC1; IRIS; PSCP; RNF53; Breast Cancer 1,Early Onset; RING finger protein 53
• Applicable Secondary Antibody
  SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
• Manual link
• Delivery condition
  4℃ with ice bags
• Storage instructions
  Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by Cloud Clone Corp. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cloud Clone Corp adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

#

• Gene target
  Breast   Cancer   Susceptibility   Protein   BRCA1   20ug  
• Gene symbol
  BRCA1, BRCA1P1
• Short name
  Rabbit polyclonal-Anti-Breast Cancer Susceptibility Protein 1 (BRCA1)-20ug
• Technique
  Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit, Rabbits
• Alternative name
  production species: rabbit polyclonal-Antibody toBreast Cancer Susceptibility Protein 1 (breast cancer 1, early onset)-20ug
• Alternative technique
  polyclonals, rabbit-anti, antibodies
• Alternative to gene target
  breast cancer 1, early onset, BRCAI and BRCC1 and BROVCA1 and IRIS and PNCA4 and PPP1R53 and PSCP and RNF53, BRCA1 and IDBG-52172 and ENSG00000012048 and 672, androgen receptor binding, nuclei, Brca1 and IDBG-212218 and ENSMUSG00000017146 and 12189, BRCA1 and IDBG-640630 and ENSBTAG00000022520 and 353120
• Tissue
  breast
• Disease
  cancer

Gene info

• Identity
  HGNC:1100
• Gene
  BRCA1
• Long gene name
  BRCA1 DNA repair associated
• Synonyms gene name
  • breast cancer 1, early onset
  • breast cancer 1
• Synonyms
  • RNF53
  • BRCC1
  • PPP1R53
  • FANCS
• Synonyms name
  • BRCA1/BRCA2-containing complex, subunit 1
  • protein phosphatase 1, regulatory subunit 53
  • Fanconi anemia, complementation group S
• GenBank acession
  • U14680
• Locus
  17q21.31
• Discovery year
  1991-02-20
• Entrez gene record
  672
• Pubmed identfication
  • 1676470
  • 25472942
• RefSeq identity
  • NM_007294
• Classification
  • Ring finger proteins
  • Protein phosphatase 1 regulatory subunits
  • BRCA1 A complex
  • BRCA1 B complex
  • BRCA1 C complex
  • FA complementation groups
• VEGA ID
  OTTHUMG00000157426
• Locus Specific Databases
  • Breast Cancer
  • Fanconi Anaemia Mutation Database
  • BRCA1 database at LOVD-China
  • Global Variome shared LOVD
  • LOVD - Leiden Open Variation Database
  • LRG_292

Gene info

• Identity
  HGNC:28470
• Gene
  BRCA1P1
• Long gene name
  BRCA1 pseudogene 1
• Synonyms
  • LBRCA1
  • PsiBRCA1
  • pseudo-BRCA1
• Synonyms name
  • like-BRCA1
• Locus
  17q21.31
• Discovery year
  2005-05-26
• Entrez gene record
  394269
• Pubmed identfication
  • 11880951
  • 8954804
  • 10205276
• RefSeq identity
  • NG_003183

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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