OVA Conjugated Wilms Tumor Protein (WT1)
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Catalog number
CPF116Ra21
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Price
Please ask
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Size
10ug
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Rattus norvegicus (Rat)
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Item Name
Wilms Tumor Protein
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Alternative Names
WAGR; GUD; WIT-2; WT33
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Research Area
Tumor immunity;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
> 90%
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Protein length
Thr402-Ser415
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Tag
N-terminal His Tag
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Expression System
Protein conjugation
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Application
Immunogen; SDS-PAGE; WB.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Gene symbol
WT1-AS, WT1
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Short name
OVA Conjugated Wilms Tumor Protein (WT1)
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Technique
antibody Conjugates
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Host
Protein conjugation
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Species
Rattus norvegicus (Rat)
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Alternative name
OVA coupled Wilms Tumor Protein (Wilms tumor 1)
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Alternative to gene target
Wilms tumor 1, AWT1 and EWS-WT1 and GUD and NPHS4 and WAGR and WIT-2 and WT33, WT1 and IDBG-37982 and ENSG00000184937 and 7490, C2H2 zinc finger domain binding, nuclei, Wt1 and IDBG-194872 and ENSMUSG00000016458 and 22431, WT1 and IDBG-636230 and ENSBTAG00000047268 and 782183
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Tissue
tumor
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Gene info
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Identity
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Gene
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Long gene name
WT1 antisense RNA
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Synonyms gene
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Synonyms gene name
- Wilms tumor upstream neighbor 1
- WT1 antisense RNA (non-protein coding)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2005-10-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
WT1 transcription factor
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Synonyms gene
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Synonyms gene name
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Synonyms
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Locus
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Discovery year
1989-04-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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