OVA Conjugated Wilms Tumor Protein (WT1)
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Catalog numberCPF116Hu21
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Price:
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Size10ug
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SourceProtein conjugation
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Predicted Molecular Mass KDNA
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Accurate Molecular Mass KDNA
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Organism speciesHomo sapiens (Human)
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Item NameWilms Tumor Protein
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Alternative NamesWAGR; GUD; WIT-2; WT33
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Research AreaTumor immunity;
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Buffer FormulationPBS, pH7.4.
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TraitsFreeze-dried powder
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Purity> 90%
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Protein lengthThr402-Ser415
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TagN-terminal His Tag
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Expression SystemProtein conjugation
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ApplicationImmunogen; SDS-PAGE; WB.
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GeneOvalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Gene symbolWT1-AS, WT1
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Short nameOVA Conjugated Wilms Tumor Protein (WT1)
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Techniqueantibody Conjugates
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HostProtein conjugation
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SpeciesHomo sapiens (Human)
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Alternative nameOVA coupled Wilms Tumor Protein (Wilms tumor 1)
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Alternative to gene targetWilms tumor 1, AWT1 and EWS-WT1 and GUD and NPHS4 and WAGR and WIT-2 and WT33, WT1 and IDBG-37982 and ENSG00000184937 and 7490, C2H2 zinc finger domain binding, nuclei, Wt1 and IDBG-194872 and ENSMUSG00000016458 and 22431, WT1 and IDBG-636230 and ENSBTAG00000047268 and 782183
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameWT1 antisense RNA
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Synonyms gene
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Synonyms gene name
- Wilms tumor upstream neighbor 1
- WT1 antisense RNA (non-protein coding)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-10-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameWT1 transcription factor
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Synonyms gene
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Synonyms gene name
- Wilms tumor 1
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Synonyms
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Locus
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Discovery year1989-04-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data