OVA Conjugated Uncoupling Protein 1, Mitochondrial (UCP1)
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Catalog number
CPF557Hu21
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Price
Please ask
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Size
50ug
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Homo sapiens (Human)
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Item Name
Uncoupling Protein 1, Mitochondrial
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Alternative Names
SLC25A7; UCP; Thermogenin; Solute carrier family 25 member 7
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Research Area
Signal transduction;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
> 90%
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Protein length
Cys288-Met303
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Tag
N-terminal His Tag
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Expression System
Protein conjugation
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Application
Immunogen; SDS-PAGE; WB.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Gene symbol
UCP1
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Short name
OVA Conjugated Uncoupling Protein 1, Mitochondrial (UCP1)
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Technique
antibody Conjugates
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Host
Protein conjugation
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Species
Homo sapiens (Human)
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Alternative name
OVA coupled Uncoupling Protein 1, Mitochondrial (uncoupling protein 1 (mitochondrial, proton carrier))
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Alternative to gene target
uncoupling protein 1 (mitochondrial, proton carrier), SLC25A7 and UCP, UCP1 and IDBG-38859 and ENSG00000109424 and 7350, oxidative phosphorylation uncoupler activity, Plasma membranes, Ucp1 and IDBG-171838 and ENSMUSG00000031710 and 22227, UCP1 and IDBG-629680 and ENSBTAG00000004647 and 101910176,281561
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Tissue
mitochondrial
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Gene info
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Identity
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Gene
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Long gene name
uncoupling protein 1
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Synonyms gene
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Synonyms gene name
- uncoupling protein 1 (mitochondrial, proton carrier)
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Synonyms
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GenBank acession
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Locus
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Discovery year
1991-08-19
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
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Tree numbers
- E01.370.225.812.735.830
- E05.200.812.735.830
- E05.478.566.380.810
- E05.478.566.639.810
- E05.478.594.760.830
- E05.601.470.380.810
- E05.601.470.639.810
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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