OVA Conjugated Proteolipid Protein 2, Colonic Epithelium Enriched (PLP2)

• Catalog number
  CPG511Hu21-500ug
• Price
  Please ask
• Size
  500ug

• Description
  Recombinant Human Proteolipid Protein 2, Colonic Epithelium Enriched expressed in: chemical synthesis
• Specifications
  Host species: Homo sapiens (Human); Expression system: chemical synthesis; Expression region: Inquire; Purity: > 90%; Endotoxin level:
• Additional_information
  Uniprot ID: Q04941; Buffer composition: PBS, pH 7.4.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): Inquire; Isoelectric Point: Inquire
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Gene
  Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

• Gene target
  OVA   Conjugated   Proteolipid   Protein   Colonic   Epithelium   Enriched   PLP2  
• Gene symbol
  PLP2
• Short name
  OVA Conjugated Proteolipid Protein 2, Colonic Epithelium Enriched (PLP2)
• Technique
  antibody Conjugates
• Alternative name
  OVA coupled Proteolipid Protein 2, Colonic Epithelium Enriched (proteolipid protein 2 (colonic epithelium-enriched))
• Alternative to gene target
  proteolipid protein 2 (colonic epithelium-enriched), A4 and A4LSB, PLP2 and IDBG-65641 and ENSG00000102007 and 5355, chemokine binding, Plasma membranes

Gene info

• Identity
  HGNC:9087
• Gene
  PLP2
• Long gene name
  proteolipid protein 2
• Synonyms gene name
  • proteolipid protein 2 (colonic epithelium-enriched)
• Synonyms
  • A4
  • A4-LSB
  • MGC126187
• Synonyms name
  • A4 differentiation-dependent protein
• GenBank acession
  • L09604
• Locus
  Xp11.23
• Discovery year
  1998-05-05
• Entrez gene record
  5355
• Pubmed identfication
  • 8470895
  • 7622043
• RefSeq identity
  • NM_002668
• Classification
  • MARVEL domain containing
• VEGA ID
  OTTHUMG00000021513
• Locus Specific Databases
  • Global Variome shared LOVD

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