OVA Conjugated p53 Upregulated Modulator Of Apoptosis (PUMA)
-
Catalog number
CPB909Hu21-50ug
-
Price
Please ask
-
Size
50ug
-
-
Description
Recombinant Human p53 Upregulated Modulator Of Apoptosis expressed in: chemical synthesis
-
Specifications
Host species: Homo sapiens (Human); Expression system: chemical synthesis; Expression region: Inquire; Purity: > 90%; Endotoxin level:
-
Additional_information
Uniprot ID: Inquire; Buffer composition: PBS, pH 7.4.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): Inquire; Isoelectric Point: Inquire
-
Storage_and_shipping
Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
-
Notes
Research Use Only.
-
Additional description
This 1 is suited for programmed cell-death studies.
-
Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
-
Gene target
-
Gene symbol
BBC3, HCAR2
-
Short name
OVA Conjugated p53 Upregulated Modulator Of Apoptosis (PUMA)
-
Technique
apoptosis, apoptosis pathway, antibody Conjugates
-
Alternative name
OVA coupled p53 Upregulated Modulator on programmed cellular destruction (PUMA)
-
Alternative technique
celldeath
-
Gene info
-
Identity
-
Gene
-
Long gene name
BCL2 binding component 3
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2002-07-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- BCL2 homology region 3 (BH3) only
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
Similar products