OVA conjugated Islet Amyloid Polypeptide (IAPP)
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Catalog number
CPA812Hu22
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Price
Please ask
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Size
50ug
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Homo sapiens (Human)
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Item Name
Islet Amyloid Polypeptide
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Alternative Names
IAP; DAP; Amylin; Insulinoma Amyloid Polypeptide; Diabetes-associated peptide
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Research Area
Metabolic pathway;Endocrinology;Hepatology;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
>90%
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Protein length
NA
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Tag
No tag
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Expression System
Protein Conjugation
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Application
Immunogen; SDS-PAGE; WB
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Gene symbol
IAPP
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Short name
OVA conjugated Islet Amyloid Polypeptide (IAPP)
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Technique
antibody Conjugates
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Host
chemical synthesis
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Species
Homo sapiens (Human)
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Alternative name
OVA coupled Islet Amyloid multipeptide (islet amyloid polypeptide)
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Alternative to gene target
islet amyloid polypeptide, DAP and IAP, IAPP and IDBG-22720 and ENSG00000121351 and 3375, identical protein binding, Extracellular, Iapp and IDBG-196723 and ENSMUSG00000041681 and 15874, IAPP and IDBG-638993 and ENSBTAG00000010530 and 100138011
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Gene info
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