OVA Conjugated Immunoglobulin M (IgM)
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Catalog number
CPA543Mu21
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Price
Please ask
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Size
10ug
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Source
Protein conjugation
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Predicted Molecular Mass KD
NA
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Accurate Molecular Mass KD
NA
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Organism species
Mus musculus (Mouse)
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Item Name
Immunoglobulin M
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Alternative Names
IGHM; Immunoglobulin Heavy Constant Mu; Ig mu chain C region
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Research Area
Infection immunity;Immune molecule;Hematology;
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Buffer Formulation
PBS, pH7.4.
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Traits
Freeze-dried powder
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Purity
>90%
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Protein length
NA
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Tag
No tag
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Expression System
Protein Conjugation
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Application
Immunogen; SDS-PAGE; WB
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Properties
Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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Gene target
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Short name
OVA Conjugated Immunoglobulin M (IgM)
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Technique
IgM, antibody Conjugates, IgMs
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Host
chemical synthesis
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Isotype
IgM, IgM
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Species
Mus musculus (Mouse)
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Alternative name
OVA coupled Immunoglobulin M (Immunoglobulin M)
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Alternative technique
immunoglobulin-m
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