OVA Conjugated Fatty Acid Desaturase 1 (FADS1)

Source

Protein conjugation
Predicted Molecular Mass KD

NA
Accurate Molecular Mass KD

NA
Organism species

Mus musculus (Mouse)
Item Name

Fatty Acid Desaturase 1
Alternative Names

D5D; FADS6; FADSD5; LLCDL1; TU12; Delta-5 Desaturase; Delta(5) fatty acid desaturase
Research Area

Enzyme & Kinase;Metabolic pathway;
Buffer Formulation

PBS, pH7.4.
Traits

Freeze-dried powder
Purity

> 90%
Protein length

Glu25-Arg37
Tag

N-terminal His Tag
Expression System

Protein conjugation
Application

Immunogen; SDS-PAGE; WB.
Manual link
Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.