OVA conjugated Elastase 1, Pancreatic (ELA1)

Source

Protein conjugation
Predicted Molecular Mass KD

NA
Accurate Molecular Mass KD

NA
Organism species

Homo sapiens (Human)
Item Name

Elastase 1, Pancreatic
Alternative Names

PE; CELA1; Chymotrypsin-Like Elastase Family,Member 1
Research Area

Enzyme & Kinase;Infection immunity;Hepatology;
Buffer Formulation

PBS, pH7.4.
Traits

Freeze-dried powder
Purity

>90%
Protein length

NA
Tag

No tag
Expression System

Protein Conjugation
Application

Immunogen; SDS-PAGE; WB
Manual link
Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

Identity

HGNC:3308
Gene

CELA1
Long gene name

chymotrypsin like elastase 1
Synonyms gene
- ELA1
Synonyms gene name
- elastase 1, pancreatic
- chymotrypsin-like elastase family, member 1
Locus

12q13.13
Discovery year

2001-06-22
Entrez gene record

1990
RefSeq identity
- NM_001971
Classification
- Chymotrypsin like elastases
VEGA ID

OTTHUMG00000167523