Mouse monoclonal-Anti- Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)-2X20ug
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Catalog numberMAA139Hu22-2X20ug
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PricePlease ask
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Size2X20ug
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Organism SpeciesHomo sapiens (Human)
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SourceMonoclonal antibody preparation
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PurificationProtein A + Protein G affinity chromatography
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Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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Item NameTumor Necrosis Factor Related Apoptosis Inducing Ligand
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ImmunogenRPA139Hu01-Recombinant Tumor Necrosis Factor Related Apoptosis Inducing Ligand (TRAIL)
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Image number5
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Species reactivityHuman
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Sequence of immunogenVal114~Gly281
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AplicationWB,IHC
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ClonalityMouse monoclonal
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Concentration1mg/ml
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Alternative NamesCD253; TNFSF10; APO2L; Apo2-L; TL2; TRAIL; Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand
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Applicable Secondary AntibodySAA544Mu08, SAA544Mu09, SAA544Mu07, SAA544Mu19, SAA544Mu18, SAA544Mu17
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Delivery condition4℃ with ice bags
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Storage instructionsAvoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This 1 is suited for programmed cell-death studies. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolTNFSF10, TNFRSF10B
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Short nameMouse monoclonal-Anti- Tumor Necrosis Factor Apoptosis Ligand (TRAIL)-2X20ug
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TechniqueMouse monoclonal, apoptosis, Mouse, anti, antibody to, apoptosis pathway, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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SpeciesMouse, Mouses
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Alternative nameMouse monoclonal-antibody to- Tumor Necrosis Factor Related programmed cellular destruction Inducing Ligand (TRAIL)-2X20ug
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Alternative techniquecelldeath, murine, antibodies
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 10
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Pubmed identfication
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 10b
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 10b
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data