Eukaryotic Interleukin 1 Receptor Antagonist (IL1RA)
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Catalog numberEPA223Hu61
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PricePlease ask
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Size50ug
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SourceEukaryotic expression
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Predicted Molecular Mass KD18.7kDa
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Accurate Molecular Mass KD22/25/27kDa
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Organism speciesHomo sapiens (Human)
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Item NameInterleukin 1 Receptor Antagonist
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Alternative NamesIL1RN; IL1-RA; ICIL1RA; IL1ra3; IL1F3; IRAP;IL-1RA; Interleukin-1 Family Member 3; IL1 inhibitor; Anakinra
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Research AreaCytokine;Signal transduction;Infection immunity;
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Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
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TraitsFreeze-dried powder
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Isoelectric Point5.4
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Purity> 95%
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Protein lengthArg26~Glu177
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TagN-terminal His Tag
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Expression SystemEukaryotic expression
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ApplicationPositive Control; Immunogen; SDS-PAGE; WB.
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DescriptionThe antagonist receptor ligand binding will be in contrast with agonist activity. Cloud Clone Corp produces more antagonist and receptor related products as 1. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolIL1R1, IL1RN
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Short nameEukaryotic Interleukin 1 Receptor Antagonist (IL1RA)
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Host293F cell
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SpeciesHomo sapiens (Human)
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Alternative nameEukaryotic Interleukin 1 Receptor Antagonist (IL1RA)
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 receptor type 1
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Synonyms gene
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Synonyms gene name
- interleukin 1 receptor, type I
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-06-27
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Entrez gene record
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Pubmed identfication
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Classification
- I-set domain containing
- Interleukin receptors
- TIR domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 receptor antagonist
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-11-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
- Interleukin receptors
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VEGA ID
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Locus Specific Databases