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Organism Species
Homo sapiens (Human)
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Source
Polyclonal antibody preparation
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Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
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Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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Item Name
Fc Fragment Of IgG Receptor Transporter Alpha
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Immunogen
RPJ114Hu01-Recombinant Fc Fragment Of IgG Receptor Transporter Alpha (FcgRT)
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Image number
3
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Species reactivity
Human
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Sequence of immunogen
FcgRT (Ala24~Ala365)
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Aplication
WB,IHC
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Clonality
Rabbit polyclonal
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Concentration
500ug/ml
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Alternative Names
FCRN; Neonatal Fc receptor; IgG receptor FcRn large subunit p51
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Applicable Secondary Antibody
SAA544Rb59, SAA544Rb58, SAA544Rb57, SAA544Rb18, SAA544Rb19
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Delivery condition
4℃ with ice bags
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Storage instructions
Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
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Description
The Anti-Fc Of IgG Receptor Transporter Alpha (FcgRT)-Rabbit polyclonal Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by Cloud Clone Corp. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cloud Clone Corp adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Group
Polyclonals and antibodies
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Latin name
Oryctolagus cuniculus
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French translation
anticorps
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Gene target
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Gene symbol
FCGRT
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Short name
Anti-Fc Of IgG Receptor Transporter Alpha (FcgRT)-Rabbit polyclonal Antibody
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Technique
Polyclonal, Antibody, Rabbit, anti-, anti, IgG, FC, antibody to, antibodies, antibodies against human proteins, antibodies for, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Isotype
IgG, Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common. IgG
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Alternative name
Antibody toFc Fragment on Immunoglobulin G Receptor Transporter a (fragment c fragment on Immunoglobulin G, receptor, transporter, alpha)-production species: rabbit polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies, rabbit-anti, immunoglobulins
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Alternative to gene target
Fc fragment of IgG, receptor, transporter, alpha, alpha-chain and FCRN, FCGRT and IDBG-63001 and ENSG00000104870 and 2217, beta-2-microglobulin binding, Plasma membranes, Fcgrt and IDBG-181534 and ENSMUSG00000003420 and 14132, FCGRT and IDBG-640575 and ENSBTAG00000013926 and 338062
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