Adrenergic Receptor Beta Kinase 1 (ADRbK1) Polyclonal Antibody (Human), Cy3

• Catalog number
  PAC189Hu01-200ul-Cy3
• Price
  Please ask
• Size
  200ul

• Description
  A Rabbit polyclonal antibody against Human Adrenergic Receptor Beta Kinase 1 (ADRbK1). This antibody is labeled with Cy3.
• Specifications
  Host: Rabbit; Species Reactivity: Human; Clonality: polyclonal; Tested applications: WB, IHC; Concentration: 500ug/ml; Isotype: IgG; Conjugation: Cy3
• Additional_information
  Sequence of the immunogen: ADRbK1 (Asp398~Leu640); Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
• Storage_and_shipping
  Upon receipt, store at -20°C or -80°C. Prepare working aliqotes prior to storage to avoid repeated freeze-thaw cycles.
• Notes
  Research Use Only.
• Properties
  If you buy Antibodies supplied by Cloud Clone Corp they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Adrenergic Receptor Beta Kinase 1 (ADRbK1) Polyclonal Antibody ( ), can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Cloud Clone Corp antibody is well suited for fluorescent microscopy. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Conjugation
  cy3 conjugation kit
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Adrenergic   Receptor   Beta   Kinase   ADRbK1  
• Gene symbol
  GRK2
• Short name
  Adrenergic Receptor Beta Kinase 1 (ADRbK1) Polyclonal Antibody ( ),
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Cy3
• Species
  Human, Humans
• Alternative name
  Adrenergic Receptor b phosphorylation catalyst 1 (adrenergic, b, receptor phosphorylation catalyst 1) polyclonal (antibody to-) (H. sapiens), cyanine 3
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  adrenergic, beta, receptor kinase 1, BARK1 and BETA-ARK1 and GRK2, ADRBK1 and IDBG-59896 and ENSG00000173020 and 156, transferase activity, Plasma membranes, Adrbk1 and IDBG-129419 and ENSMUSG00000024858 and 110355, ADRBK1 and IDBG-644669 and ENSBTAG00000005832 and 282682

Gene info

• Identity
  HGNC:289
• Gene
  GRK2
• Long gene name
  G protein-coupled receptor kinase 2
• Synonyms gene
  • ADRBK1
• Synonyms gene name
  • adrenergic, beta, receptor kinase 1
• Synonyms
  • BARK1
• GenBank acession
  • X61157
• Locus
  11q13.2
• Discovery year
  1992-03-25
• Entrez gene record
  156
• Pubmed identfication
  • 2037065
• RefSeq identity
  • NM_001619
• Classification
  • Pleckstrin homology domain containing
  • AGC family kinases
• VEGA ID
  OTTHUMG00000167104

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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