Active Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9)

• Catalog number
  APB527Hu01
• Price
  Please ask
• Size
  10ug

• Source
  NA
• Predicted Molecular Mass KD
  13.6kDa
• Accurate Molecular Mass KD
  16kDa
• Organism species
  Homo sapiens (Human)
• Item Name
  Tumor Necrosis Factor Receptor Superfamily, Member 9
• Alternative Names
  CD137; CDw137; 4-1BB; ILA; Induced By Lymphocyte Activation; T-cell antigen 4-1BB homolog
• Research Area
  CD & Adhesion molecule;
• Buffer Formulation
  20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Isoelectric Point
  8.3
• Purity
  > 97%
• Protein length
  Asn40~Glu153
• Tag
  N-terminal His Tag
• Expression System
  NA
• Application
  Cell culture; Activity Assays.
• Manual link
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Active   Tumor   Necrosis   Factor   Receptor   Superfamily   Member   TNFRSF9  
• Gene symbol
  TNFRSF9
• Short name
  Active Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9)
• Host
  NA
• Species
  Homo sapiens (Human)
• Alternative name
  functionnal Tumor Necrosis Factor Receptor supergroup, Member 9 (tumor necrosis factor receptor superfamily, member 9)
• Alternative to gene target
  tumor necrosis factor receptor superfamily, member 9, 4-1BB and CD137 and CDw137 and ILA, TNFRSF9 and IDBG-88268 and ENSG00000049249 and 3604, cytokine binding, Extracellular, Tnfrsf9 and IDBG-205902 and ENSMUSG00000028965 and 21942, BT.49346 and IDBG-633668 and ENSBTAG00000003313 and 520341
• Tissue
  tumor

Gene info

• Identity
  HGNC:11924
• Gene
  TNFRSF9
• Long gene name
  TNF receptor superfamily member 9
• Synonyms gene
  • ILA
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 9
• Synonyms
  • CD137
  • 4-1BB
• GenBank acession
  • L12964
• Locus
  1p36.23
• Discovery year
  1996-06-12
• Entrez gene record
  3604
• Pubmed identfication
  • 8262389
  • 8639902
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000001223

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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