Active Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14)

• Catalog number
  APD926Hu01-10ug
• Price
  Please ask
• Size
  10ug

• Description
  Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 14 expressed in: E.coli
• Specifications
  Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Ser41~Ser209; Purity: > 95%; Endotoxin level:
• Additional_information
  Uniprot ID: Q92956; Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 21.6kDa; Isoelectric Point: 6.8
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Active   Tumor   Necrosis   Factor   Receptor   Superfamily   Member   TNFRSF14  
• Gene symbol
  TNFRSF14-AS1, TNFRSF14
• Short name
  Active Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14)
• Alternative name
  functionnal Tumor Necrosis Factor Receptor supergroup, Member 14 (tumor necrosis factor receptor superfamily, member 14)
• Alternative to gene target
  tumor necrosis factor receptor superfamily, member 14, ATAR and CD270 and HVEA and HVEM and LIGHTR and TR2, TNFRSF14 and IDBG-86399 and ENSG00000157873 and 8764, ubiquitin protein ligase binding, Cell surfaces, Tnfrsf14 and IDBG-207237 and ENSMUSG00000042333 and 230979
• Tissue
  tumor

Gene info

• Identity
  HGNC:26966
• Gene
  TNFRSF14-AS1
• Long gene name
  TNFRSF14 antisense RNA 1
• Synonyms
  • ENST00000416860.2
• Locus
  1p36.32
• Discovery year
  2017-04-27
• Entrez gene record
  115110
• Pubmed identfication
  • 28418905
• RefSeq identity
  • NR_037844
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:11912
• Gene
  TNFRSF14
• Long gene name
  TNF receptor superfamily member 14
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
  • tumor necrosis factor receptor superfamily, member 14
• Synonyms
  • HVEM
  • ATAR
  • TR2
  • LIGHTR
  • HVEA
  • CD270
• Synonyms name
  • herpesvirus entry mediator
• GenBank acession
  • U70321
• Locus
  1p36.32
• Discovery year
  1998-12-04
• Entrez gene record
  8764
• Pubmed identfication
  • 8898196
  • 9162061
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000000792

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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