Active Suppressors Of Cytokine Signaling 3 (SOCS3)
#
-
Catalog numberAPB684Mu01
-
Price:
-
Size1mg
-
-
SourceNA
-
Predicted Molecular Mass KD26.0kDa
-
Accurate Molecular Mass KD26kDa
-
Organism speciesMus musculus (Mouse)
-
Item NameSuppressors Of Cytokine Signaling 3
-
Alternative NamesATOD4; CIS3; Cish3; MGC71791; SOCS-3; SSI-3; SSI3; Cytokine-inducible SH2 protein 3; STAT-induced STAT inhibitor 3
-
Research AreaSignal transduction;Tumor immunity;Immune molecule;Hepatology;
-
Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
-
TraitsFreeze-dried powder
-
Isoelectric Point8.7
-
Purity> 97%
-
Protein lengthMet1~Leu225
-
TagN-terminal His Tag
-
Expression SystemNA
-
ApplicationCell culture; Activity Assays.
-
DescriptionCytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
-
Gene target
-
Gene symbolSOCS3-DT, SOCS3
-
Short nameActive Suppressors Of Cytokine Signaling 3 (SOCS3)
-
HostE. coli
-
SpeciesMus musculus (Mouse)
-
Alternative namefunctionnal Suppressors on Cytokine Signaling 3 (suppressor on cytokine signaling 3)
-
Alternative to gene targetsuppressor of cytokine signaling 3, ATOD4 and CIS3 and Cish3 and SOCS-3 and SSI-3 and SSI3, SOCS3 and IDBG-70676 and ENSG00000184557 and 9021, protein binding, Cytoplasm, Socs3 and IDBG-214604 and ENSMUSG00000053113 and 12702, SOCS3 and IDBG-647946 and ENSBTAG00000008441 and 282081
-
Gene info
-
Identity
-
Gene
-
Long gene nameSOCS3 divergent transcript
-
Locus
-
Discovery year2020-10-19
-
Entrez gene record
-
RefSeq identity
-
Classification
- Divergent transcripts
Gene info
-
Identity
-
Gene
-
Long gene namesuppressor of cytokine signaling 3
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-11-13
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Suppressors of cytokine signaling
- SH2 domain containing
-
VEGA ID
-
Locus Specific Databases