Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

• Catalog number
  APA855Mu61-10ug
• Price
  Please ask
• Size
  10ug

• Description
  Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells
• Specifications
  Host species: Mus musculus (Mouse); Expression system: Available from E.coli, Yeast, Baculovirus and Mammalian cells; Expression region: Arg72~Asp316; Purity: > 90%; Endotoxin level:
• Additional_information
  Uniprot ID: O35235; Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 29.2kDa; Isoelectric Point: 7.1
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Active   Receptor   Activator   Factor   Kappa   Ligand   RANkL  
• Short name
  Active Receptor Activator Of Factor Kappa B Ligand (RANkL)
• Alternative name
  functionnal Receptor Activator on Nuclear Factor Kappa B Ligand (RANkL)

Similar products