Active Interleukin 1 Receptor Antagonist (IL1RA)

• Catalog number
  APA223Hu01-500ug
• Price
  Please ask
• Size
  500ug

• Description
  Recombinant Human Interleukin 1 Receptor Antagonist expressed in: E.coli
• Specifications
  Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Arg26~Glu177; Purity: > 95%; Endotoxin level:
• Additional_information
  Uniprot ID: P18510; Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 18.4kDa; Isoelectric Point: 6
• Storage_and_shipping
  Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
• Notes
  Research Use Only.
• Additional description
  The antagonist receptor ligand binding will be in contrast with agonist activity. Cloud Clone Corp produces more antagonist and receptor related products as 1. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Active   Interleukin   Receptor   Antagonist   IL1RA  
• Gene symbol
  IL1R1, IL1RN
• Short name
  Active Interleukin 1 Receptor Antagonist (IL1RA)
• Alternative name
  functionnal Interleukin 1 Receptor Antagonist (IL1RA)

Gene info

• Identity
  HGNC:5993
• Gene
  IL1R1
• Long gene name
  interleukin 1 receptor type 1
• Synonyms gene
  • IL1R
  • IL1RA
• Synonyms gene name
  • interleukin 1 receptor, type I
• Synonyms
  • D2S1473
  • CD121A
• Synonyms name
  • interleukin-1 receptor, type I
• GenBank acession
  • M27492
• Locus
  2q11.2-q12.1
• Discovery year
  1990-06-27
• Entrez gene record
  3554
• Pubmed identfication
  • 1833184
  • 10191101
• Classification
  • I-set domain containing
  • Interleukin receptors
  • TIR domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000130783

Gene info

• Identity
  HGNC:6000
• Gene
  IL1RN
• Long gene name
  interleukin 1 receptor antagonist
• Synonyms
  • IL1RA
  • ICIL-1RA
  • IL1F3
  • IRAP
  • IL-1RN
  • MGC10430
• Synonyms name
  • interleukin-1 receptor antagonist protein
  • intracellular interleukin-1 receptor antagonist
• GenBank acession
  • M55646
• Locus
  2q14.1
• Discovery year
  1990-11-20
• Entrez gene record
  3557
• Pubmed identfication
  • 1386337
  • 8432529
• RefSeq identity
  • NM_173841
• Classification
  • Interleukins
  • Interleukin receptors
• VEGA ID
  OTTHUMG00000131341
• Locus Specific Databases
  • LRG_188

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