100ug-Anti- Stem Cell Factor Receptor (SCFR)

• Catalog number
  MAA121Ra21-100ug
• Price
  Please ask
• Size
  100ug

• Organism Species
  Rattus norvegicus (Rat)
• Source
  Monoclonal antibody preparation
• Purification
  Protein A + Protein G affinity chromatography
• Buffer Formulation
  PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
• Item Name
  Stem Cell Factor Receptor
• Immunogen
  -
• Image number
  5
• Species reactivity
  Rat
• Sequence of immunogen
  -
• Aplication
  WB,IHC
• Clonality
  Mouse monoclonal
• Concentration
  1mg/ml
• Alternative Names
  CD117; KIT; C-Kit; PBT; p145 c-Kit; C-Kit Receptor; Tyrosine-Protein Kinase; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Piebald Trait
• Applicable Secondary Antibody
  SAA544Mu08, SAA544Mu09, SAA544Mu07, SAA544Mu19, SAA544Mu18, SAA544Mu17
• Manual link
• Delivery condition
  4℃ with ice bags
• Storage instructions
  Avoid repeated freeze/thaw cycles. Store at 4 ℃ for frequent use. Aliquot and store at -20℃ for 12 months.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Test
  Stem cell factors and stem cell growth factors will produce stem cells or be part of a transdifferentiation process to produce other cells. A cell can transdifferentiate by going back to the naive stem cell stadium or directly into the other cell, helped by the stem cell and transdifferentiationf actors. Stem cell growth factors or stem cell factors are mostly used to produce iPSCs or induced pluripotent stem cells by Jamaka or Thomson factors by using for example 5 Lenti-III-CMV viruses, expressing the Yamanaka iPSC factor set (Oct4, Sox2, Nanog and Lin28) + GFP positive control. Trans differentiation will omit the stem cell stadium but stem cell factors sill play an important role in trans differentiation strategies.

• Gene target
  100ug   Stem   Factor   Receptor   SCFR  
• Gene symbol
  KIT
• Short name
  100ug-Anti- Stem Factor Receptor (SCFR)
• Technique
  anti, antibody to
• Host
  Mouse
• Alternative name
  100ug-antibody to- progenitor cellular Factor Receptor (SCFR)
• Alternative technique
  antibodies
• Tissue
  cell, stem

Gene info

• Identity
  HGNC:6342
• Gene
  KIT
• Long gene name
  KIT proto-oncogene, receptor tyrosine kinase
• Synonyms gene
  • PBT
• Synonyms gene name
  • piebald trait
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
• Synonyms
  • CD117
  • SCFR
  • C-Kit
• Synonyms name
  • mast/stem cell growth factor receptor Kit
• GenBank acession
  • S67773
• Locus
  4q12
• Discovery year
  1986-01-01
• Entrez gene record
  3815
• Pubmed identfication
  • 9027509
• RefSeq identity
  • NM_000222
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000128713
• Locus Specific Databases
  • LRG_307

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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