ViraSafe Universal Lentiviral Expression System, Ecotropic

Shipping Temp

Blue Ice
Storage Temp

-20ºC
Category Product Type

Kit
URL link to datasheet
URL link to SDS

more (VPK-205 through VPK-222-xxx) GHS.pdf
UNSPSC

41105908
Product Line

Viral Expression
Short Description

Lentivirus based on HIV-1 provides a powerful means for gene expression because it can infect both dividing and non-dividing cells. Other 3rd generation lentiviral packaging systems provide a reduced risk of replication-competent virus, but a small risk remains. Our ViraSafe™ Lentivirus Expression Complete Systems provide a safer method even compared to other 3rd generation expression systems. Overlap with native HIV genes has been reduced much further, thereby substantially reducing the chance of generating replication-competent virus. The system has been engineered so that lentiviral titers remain at the levels of third generation systems. Our Ecotropic Expression Systems assemble lentiviruses with an ecotropic envelope protein which will readily infect only mouse and rat cells via receptor-mediated binding, providing an additional level of safety. However, ecotropic viruses are not as stable upon freezing and will not survive ultracentrifugation procedures.
Product feature 1

Significantly reduced homology compared to other 3rd generation expression systems for added safety, without loss of titer
Product feature 2

Complete Expression System contains packaging plasmids and expression vector
Product feature 3

Cloning capacity of expression vector = 9.4 kb

Name

Virus Cultivation
Concept

Scope note: Process of growing viruses in live animals, plants, or cultured cells.
Tree numbers
- E01.370.225.875.970
- E05.200.875.970
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data