TLR10 Antibody

• Catalog number
  PA1958
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  TLR10
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human TLR10(88-102aa DLKTFEFNKELRYLD).
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the TLR10 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The TLR10 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  TLR10(Toll-like receptor 10), is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of the Toll-like receptor(TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. By genomic sequence analysis, Hasan et al.(2005) determined that the TLR10 gene is clustered with TLR1 and TLR6 on chromosome 4p14. By coimmunoprecipitation analysis, Hasan et al.(2005) found that TLR10 associated with itself and with TLR1 and TLR2, but not with MD2. Signaling studies showed that TLR10 required MYD88, but not TIRAP, TRAM(TICAM2), or TRIF(TICAM1), to activate immune system promoters. Pro674 within the TLR10 TIR domain was required to activate all promoter examined.
• Related articles
  1. Chuang, T.-H., Ulevitch, R. J. Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells. Biochim. Biophys. Acta 1518: 157-161, 2001. 2. Hasan, U., Chaffois, C., Gaillard, C., Saulnier, V., Merck, E., Tancredi, S., Guiet, C., Briere, F., Vlach, J., Lebecque, S., Trinchieri, G., Bates, E. E. M. Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J. Immun. 174: 2942-2950, 2005. 3. Kadowaki, N., Ho, S., Antonenko, S., de Waal Malefyt, R., Kastelein, R. A., Bazan, F., Liu, Y.-J. Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194: 863-869, 2001.
• Gene Name
  TLR10
• Protein Name
  Toll-like receptor 10
• Gene Full Name
  toll-like receptor 10
• Synonyms
  CD 290 antibody|CD 290 antigen antibody|CD290 antibody|CD290 antigen antibody|MGC104967 antibody|MGC126398 antibody|MGC126399 antibody|OTTHUMP00000158729 antibody|OTTHUMP00000218162 antibody|TLR10 antibody|TLR10_HUMAN antibody|Toll like receptor 10 antibody|Toll-like receptor 10 antibody|UNQ315/PRO358 antibody
• Uniprot ID
  Q9BXR5
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR10  
• Gene symbol
  TLR10
• Short name
  TLR10 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  toll-like receptor 10 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 10, TLR10 and IDBG-13548 and ENSG00000174123 and 81793, protein binding, Plasma membranes, TLR10 and IDBG-641604 and ENSBTAG00000014042 and 539791

Gene info

• Identity
  HGNC:15634
• Gene
  TLR10
• Long gene name
  toll like receptor 10
• Synonyms gene name
  • toll-like receptor 10
• Synonyms
  • CD290
• GenBank acession
  • AF296673
• Locus
  4p14
• Discovery year
  2001-04-27
• Entrez gene record
  81793
• Pubmed identfication
  • 11267672
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000128578

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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