TIAM1 Antibody

  • Catalog number
    PB10103
  • Price
    Please ask
  • Size
    0,1 mg
  • Target antigen
    TIAM1
  • Clonality
    Polyclonal antibody
  • Clone
    Polyclonal antibody
  • Raised in
    rabbit
  • Type of the antibody
    IgG polyclonal antibody
  • Product form
    freeze-dried
  • Reacts with species
    human
  • Analyses
    WB
  • Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human TIAM1 (1518-1554aa ASVDRDLQERLQATSISQRERGRKTLDSHASRMAQLK), different from the related mouse sequence by five amino acids.
  • Product configuration
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
  • Purification
    Immunogen affinity purified.
  • Solubilization
    The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
  • Storage condtions
    Keep the TIAM1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The TIAM1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    T-cell lymphoma invasion and metastasis-inducing protein 1 is a protein that in humans is encoded by the TIAM1 gene. This gene is mapped to 21q22.11. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA.
  • Related articles
    1. "Entrez Gene: TIAM1 T-cell lymphoma invasion and metastasis 1". 2. Chen H, Antonarakis SE (Nov 1995). "Localization of a human homolog of the mouse Tiam-1 gene to chromosome 21q22.1". Genomics 30 (1): 123–7. 3. Uhlenbrock K, Eberth A, Herbrand U, Daryab N, Stege P, Meier F, Friedl P, Collard JG, Ahmadian MR (Sep 2004). "The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism". Journal of Cell Science 117 (Pt 20): 4863–71.
  • Gene Name
    TIAM1
  • Protein Name
    T-lymphoma invasion and metastasis-inducing protein 1
  • Gene Full Name
    T-cell lymphoma invasion and metastasis 1
  • Synonyms
    TIAM-1 | TIAM1 | TIAM 1 | Q13009
  • Uniprot ID
    Q13009
  • Entrez GeneID
    7074
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    TIAM1  
  • Gene symbol
    TIAM1, TIAM1-AS1
  • Short name
    TIAM1 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    T-cellular lymphoma invasion and metastasis 1 (antibody to-)
  • Alternative technique
    antibodies
  • Alternative to gene target
    T-cell lymphoma invasion and metastasis 1, TIAM1 and IDBG-1597 and ENSG00000156299 and 102724932,7074, ephrin receptor binding, Cell surfaces, Tiam1 and IDBG-174466 and ENSMUSG00000002489 and 21844, BT.74139 and IDBG-630064 and ENSBTAG00000017839 and
Gene info
  • Identity
  • Gene
  • Long gene name
    TIAM Rac1 associated GEF 1
  • Synonyms gene name
    • T-cell lymphoma invasion and metastasis 1
  • Locus
  • Discovery year
    1994-04-22
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Pleckstrin homology domain containing
    • PDZ domain containing
    • Dbl family Rho GEFs
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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