splicing factor 1 Antibody

• Catalog number
  PA1864
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  splicing factor 1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, rat Predicted to work with: mouse
• Analyses
  WB,IHC-P,IHC-F,ICC
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human splicing factor 1(11-30aa DFPSKKRKRSRWNQDTMEQK), identical to the related rat and mouse sequences.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the splicing factor 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The splicing factor 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  SF1(splicing factor 1), also known as zinc finger protein 162(ZFM162), ZNF162, Transcription factor ZFM1, ZFM1, D11S636, Mammalian branch point-binding protein(BBP, mBBP), Zinc finger gene in MEN1 locus, is a protein that in humans is encoded by the SF1 gene. It is predicted 623-amino acid protein. RT-PCR was used to show expression in the thyroid gland, pancreas, adrenal gland, and ovary. All of the ZNF162 isoforms contain a KH domain, a sequence motif present in proteins playinig a major role in regulating cellular RNA metabolism.
• Related articles
  1. Toda, T., Iida, A., Miwa, T., Nakamura, Y., Imai, T. Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1). Hum. Molec. Genet. 3: 465-470, 1994. 2. Caslini, C., Spinelli, O., Cazzaniga, G., Golay, J., De Gioia, L., Pedretti, A., Breviario, F., Amaru, R., Barbui, T., Biondi, A., Introna, M., Rambaldi, A. Identification of two novel isoforms of the ZNF162 gene: a growing family of signal transduction and activator of RNA proteins. Genomics 42: 268-277, 1997.
• Gene Name
  SF1
• Protein Name
  Splicing factor 1
• Gene Full Name
  splicing factor 1
• Synonyms
  BBP antibody|D11S636 antibody|Mammalian branch point-binding protein mBBP antibody|OTTHUMP00000069749 antibody|OTTHUMP00000069750 antibody|OTTHUMP00000069752 antibody|splicing factor 1 antibody|Transcription factor ZFM1 antibody|ZFM1 antibody|Zinc finger gene in MEN1 locus antibody|Zinc finger protein 162 antibody|ZNF162 antibody
• Uniprot ID
  Q15637
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• French translation
  anticorps

• Gene target
  splicing   factor  
• Gene symbol
  SRSF1, SF3B1, SF3A1
• Short name
  splicing factor 1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  splicing factor 1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10780
• Gene
  SRSF1
• Long gene name
  serine and arginine rich splicing factor 1
• Synonyms gene
  • SFRS1
• Synonyms gene name
  • splicing factor, arginine/serine-rich 1
  • serine/arginine-rich splicing factor 1
• Synonyms
  • ASF
  • SF2
  • SRp30a
  • SF2p33
  • MGC5228
• Synonyms name
  • splicing factor 2
  • pre-mRNA-splicing factor SF2, P33 subunit
  • alternate splicing factor
  • SR splicing factor 1
• Locus
  17q22
• Discovery year
  1993-09-17
• Entrez gene record
  6426
• Pubmed identfication
  • 8530103
  • 20516191
• RefSeq identity
  • NM_006924
• Classification
  • Serine and arginine rich splicing factors
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000178781

Gene info

• Identity
  HGNC:10768
• Gene
  SF3B1
• Long gene name
  splicing factor 3b subunit 1
• Synonyms gene name
  • splicing factor 3b, subunit 1, 155kD
  • splicing factor 3b, subunit 1, 155kDa
• Synonyms
  • SAP155
  • SF3b155
  • PRPF10
  • Prp10
  • Hsh155
• GenBank acession
  • AF054284
• Locus
  2q33.1
• Discovery year
  2000-02-29
• Entrez gene record
  23451
• Pubmed identfication
  • 9585501
• Classification
  • SF3b complex
  • B-WICH chromatin-remodelling complex subunits
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000154447
• Locus Specific Databases
  • LRG_624

Gene info

• Identity
  HGNC:10765
• Gene
  SF3A1
• Long gene name
  splicing factor 3a subunit 1
• Synonyms gene name
  • splicing factor 3a, subunit 1, 120kD
  • splicing factor 3a, subunit 1, 120kDa
• Synonyms
  • SF3a120
  • SAP114
  • PRPF21
  • Prp21
• GenBank acession
  • X85237
• Locus
  22q12.2
• Discovery year
  2000-02-29
• Entrez gene record
  10291
• Pubmed identfication
  • 7489498
• RefSeq identity
  • NM_005877
• Classification
  • SF3a complex
  • U2 small nuclear ribonucleoprotein
• VEGA ID
  OTTHUMG00000151005
• Locus Specific Databases
  • LRG_622

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products