SMYD3 Antibody

  • Catalog number
    PB9893
  • Price
    Please ask
  • Size
    0,1 mg
  • Target antigen
    SMYD3
  • Clonality
    Polyclonal antibody
  • Clone
    Polyclonal antibody
  • Raised in
    rabbit
  • Type of the antibody
    IgG polyclonal antibody
  • Product form
    freeze-dried
  • Reacts with species
    human
  • Analyses
    WB,IHC-P
  • Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human SMYD3 (388-428aa QAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS), different from the related mouse sequence by one amino acid.
  • Product configuration
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
  • Purification
    Immunogen affinity purified.
  • Solubilization
    The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
  • Storage condtions
    Keep the SMYD3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
  • Tips
    The SMYD3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
  • Background
    SET and MYND domain-containing protein 3 is a protein that in humans is encoded by the SMYD3 gene. The International Radiation Hybrid Mapping Consortium mapped the SMYD3 gene to chromosome 1. This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Related articles
    1. Hamamoto, R., Furukawa, Y., Morita, M., Iimura, Y., Silva, F. P., Li, M., Yagyu, R., Nakamura, Y. SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nature Cell Biol. 6: 731-740, 2004. 2. Mazur, P. K., Reynoird, N., Khatri, P., Jansen, P. W. T. C., Wilkinson, A. W., Liu, S., Barbash, O., Van Aller, G. S., Huddleston, M., Dhanak, D., Tummino, P. J., Kruger, R. G., Garcia, B. A., Butte, A. J., Vermeulen, M., Sage, J., Gozani, O. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature 510: 283-287, 2014. 3. Tsuge, M., Hamamoto, R., Silva, F. P., Ohnishi, Y., Chayama, K., Kamatani, N., Furukawa, Y., Nakamura, Y. A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5-prime flanking region of SMYD3 is a risk factor for human cancers. Nature Genet. 37: 1104-1107, 2005.
  • Gene Name
    SMYD3
  • Protein Name
    Histone-lysine N-methyltransferase SMYD3
  • Gene Full Name
    SET and MYND domain containing 3
  • Synonyms
    bA74P14.1 (novel protein) antibody|bA74P14.1 antibody|FLJ21080 antibody|histone lysine N methyltransferase SMYD3 antibody|KMT3E antibody|MGC104324 antibody|SET and MYND domain containing 3 antibody|SET and MYND domain containing protein 3 antibody|SET and MYND domain-containing protein 3 antibody|SMYD 3 antibody|Smyd3 antibody|SMYD3 protein antibody|SMYD3_HUMAN antibody|Zinc finger MYND domain containing 1 antibody|Zinc finger MYND domain containing protein 1 antibody|Zinc finger MYND domain-containing protein 1 antibody|Zinc finger protein subfamily 3A MYND domain containing 1 antibody|Zinc finger protein, subfamily 3A (MYND domain containing), 1 antibody|ZMYND 1 antibody|ZMYND1 antibody|ZNFN3A1 antibody
  • Uniprot ID
    Q9H7B4
  • Entrez GeneID
    64754
  • Properties
    If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    SMYD3  
  • Gene symbol
    SMYD3-AS1, SMYD3-IT1, SMYD3
  • Short name
    SMYD3 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    SMYD3 (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    SMYD3 antisense RNA 1
  • Locus
  • Discovery year
    2020-03-27
  • Entrez gene record
  • Classification
    • Antisense RNAs
Gene info
  • Identity
  • Gene
  • Long gene name
    SMYD3 intronic transcript 1
  • Synonyms gene name
    • SMYD3 intronic transcript 1 (non-protein coding)
  • Locus
  • Discovery year
    2011-08-23
  • Classification
    • Intronic transcripts
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    SET and MYND domain containing 3
  • Synonyms gene
  • Synonyms gene name
    • zinc finger, MYND domain containing 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-04-06
  • Entrez gene record
  • RefSeq identity
  • Classification
    • SET domain containing
    • Lysine methyltransferases
    • Zinc fingers MYND-type
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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