SMYD3 Antibody
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Catalog numberPB9893
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PricePlease ask
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Size0,1 mg
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Target antigenSMYD3
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman
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AnalysesWB,IHC-P
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ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human SMYD3 (388-428aa QAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS), different from the related mouse sequence by one amino acid.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the SMYD3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe SMYD3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundSET and MYND domain-containing protein 3 is a protein that in humans is encoded by the SMYD3 gene. The International Radiation Hybrid Mapping Consortium mapped the SMYD3 gene to chromosome 1. This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene.
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Related articles1. Hamamoto, R., Furukawa, Y., Morita, M., Iimura, Y., Silva, F. P., Li, M., Yagyu, R., Nakamura, Y. SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells. Nature Cell Biol. 6: 731-740, 2004. 2. Mazur, P. K., Reynoird, N., Khatri, P., Jansen, P. W. T. C., Wilkinson, A. W., Liu, S., Barbash, O., Van Aller, G. S., Huddleston, M., Dhanak, D., Tummino, P. J., Kruger, R. G., Garcia, B. A., Butte, A. J., Vermeulen, M., Sage, J., Gozani, O. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature 510: 283-287, 2014. 3. Tsuge, M., Hamamoto, R., Silva, F. P., Ohnishi, Y., Chayama, K., Kamatani, N., Furukawa, Y., Nakamura, Y. A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5-prime flanking region of SMYD3 is a risk factor for human cancers. Nature Genet. 37: 1104-1107, 2005.
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Gene NameSMYD3
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Protein NameHistone-lysine N-methyltransferase SMYD3
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Gene Full NameSET and MYND domain containing 3
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SynonymsbA74P14.1 (novel protein) antibody|bA74P14.1 antibody|FLJ21080 antibody|histone lysine N methyltransferase SMYD3 antibody|KMT3E antibody|MGC104324 antibody|SET and MYND domain containing 3 antibody|SET and MYND domain containing protein 3 antibody|SET and MYND domain-containing protein 3 antibody|SMYD 3 antibody|Smyd3 antibody|SMYD3 protein antibody|SMYD3_HUMAN antibody|Zinc finger MYND domain containing 1 antibody|Zinc finger MYND domain containing protein 1 antibody|Zinc finger MYND domain-containing protein 1 antibody|Zinc finger protein subfamily 3A MYND domain containing 1 antibody|Zinc finger protein, subfamily 3A (MYND domain containing), 1 antibody|ZMYND 1 antibody|ZMYND1 antibody|ZNFN3A1 antibody
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Uniprot IDQ9H7B4
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Entrez GeneID64754
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSMYD3-AS1, SMYD3-IT1, SMYD3
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Short nameSMYD3 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameSMYD3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameSMYD3 antisense RNA 1
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Locus
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Discovery year2020-03-27
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Entrez gene record
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameSMYD3 intronic transcript 1
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Synonyms gene name
- SMYD3 intronic transcript 1 (non-protein coding)
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Locus
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Discovery year2011-08-23
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Classification
- Intronic transcripts
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSET and MYND domain containing 3
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Synonyms gene
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Synonyms gene name
- zinc finger, MYND domain containing 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-04-06
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Entrez gene record
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RefSeq identity
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Classification
- SET domain containing
- Lysine methyltransferases
- Zinc fingers MYND-type
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data