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Target antigen
SFRS3
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
mouse, rat Theoretical reactivity:human
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human SFRS3 (1-29aa MHRDSCPLDCKVYVGNLGNNGNKTELERA), identical to the related mouse and rat sequences.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the SFRS3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The SFRS3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Splicing factor, arginine/serine-rich 3, also known as SRSF3, is a protein that in humans is encoded by the SFRS3 gene. The protein encoded by this gene is a member of the serine/ arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.
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Related articles
1. "Entrez Gene: SFRS3 splicing factor, arginine/serine-rich 3". 2. Zahler AM, Lane WS, Stolk JA, Roth MB (Jun 1992). "SR proteins: a conserved family of pre-mRNA splicing factors". Genes Dev 6 (5): 837–47.
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Gene Name
SRSF3
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Protein Name
Serine/arginine-rich splicing factor 3
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Gene Full Name
serine/arginine-rich splicing factor 3
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Synonyms
arginine/serine-rich 3 antibody|Pre mRNA splicing factor SRP20 antibody|Pre-mRNA-splicing factor SRP20 antibody|Serine/arginine-rich splicing factor 3 antibody|Splicing factor antibody|Splicing factor arginine/serine rich 20 kD antibody|Splicing factor arginine/ serine rich 3 antibody|SRp20 antibody|SRSF3 antibody|SRSF3_HUMAN antibody|X16 antibody
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Uniprot ID
P84103
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Entrez GeneID
6428
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
