SCP3 Antibody

• Catalog number
  RP1035
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  SCP3
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB
• Immunogen
  E.coli-derived human SCP3 recombinant protein (Position: E18-E223). Human SCP3 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat SCP3, respectively.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the SCP3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The SCP3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.
• Related articles
  1. Martinez-Garay I, Jablonka S, Sutajova M, Steuernagel P, Gal A, Kutsche K (Sep 2002). "A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region".Genomics 80 (3): 259–67. 2. Mallon AM, Platzer M, Bate R, Gloeckner G, Botcherby MR, Nordsiek G, Strivens MA, Kioschis P, Dangel A, Cunningham D, Straw RN, Weston P, Gilbert M, Fernando S, Goodall K, Hunter G, Greystrong JS, Clarke D, Kimberley C, Goerdes M, Blechschmidt K, Rump A, Hinzmann B, Mundy CR, Miller W, Poustka A, Herman GE, Rhodes M, Denny P, Rosenthal A, Brown SD (Aug 2000). "Comparative genome sequence analysis of the Bpa/Str region in mouse and Man". Genome Res 10 (6): 758–75. 3. Miyamoto, T., Hasuike, S., Yogev, L., Maduro, M. R., Ishikawa, M., Westphal, H., Lamb, D. J. Azoospermia in patients heterozygous for a mutation in SYCP3. Lancet 362: 1714-1719, 2003.
• Gene Name
  SYCP3
• Protein Name
  Synaptonemal complex protein 3
• Gene Full Name
  synaptonemal complex protein 3
• Synonyms
  choline phosphotransferase 1 antibody|chpt1 antibody|COR 1 antibody|COR1 antibody|MGC71888 antibody|RNASCP3 antibody|SCP 3 antibody|SCP-3 antibody|SCP3 antibody|SPGF4 antibody|Sycp 3 antibody|Sycp3 antibody|SYCP3_HUMAN antibody|Synaptonemal complex protein 3 antibody
• Uniprot ID
  Q8IZU3
• Entrez GeneID
  50511
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SCP3  
• Gene symbol
  CTDSPL
• Short name
  SCP3 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  SCP3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16890
• Gene
  CTDSPL
• Long gene name
  CTD small phosphatase like
• Synonyms gene
  • C3orf8
• Synonyms gene name
  • chromosome 3 open reading frame 8
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
• Synonyms
  • HYA22
  • SCP3
  • PSR1
  • RBSP3
• Synonyms name
  • small CTD phosphatase 3
  • HYA22 protein
  • RB protein serine phosphatase from chromosome 3
• GenBank acession
  • D88153
• Locus
  3p22.2
• Discovery year
  2003-04-03
• Entrez gene record
  10217
• Pubmed identfication
  • 9179494
  • 12543795
• RefSeq identity
  • NM_005808
• Classification
  • MicroRNA protein coding host genes
  • CTD family phosphatases
• VEGA ID
  OTTHUMG00000155942

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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