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Target antigen
Rad51C
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, mouse, rat
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Rad51C (177-207aa IQHLQLIAEKHKGEEHRKALEDFTLDNILSH), different from the related mouse sequence by eight amino acids.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Rad51C Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Rad51C Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.
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Related articles
1. "Entrez Gene: RAD51C RAD51 homolog C (S. cerevisiae)". 2. Dosanjh MK, Collins DW, Fan W, Lennon GG, Albala JS, Shen Z, Schild D (March 1998). "Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes". Nucleic Acids Res. 26 (5): 1179–84.
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Gene Name
RAD51C
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Protein Name
DNA repair protein RAD51 homolog 3
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Gene Full Name
RAD51 paralog C
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Synonyms
DNA repair protein RAD51 homolog 3 antibody|MGC104277 antibody|R51H3 antibody|RA51C_HUMAN antibody|Rad 51C antibody|RAD51 homolog C (S. cerevisiae) antibody|Rad51 homolog c (S. cerevisiae), isoform CRA_b antibody|RAD51 homolog C antibody|RAD51 like protein 2 antibody|RAD51, S. cerevisiae, homolog of, C antibody|RAD51-like protein 2 antibody|RAD51C antibody|RAD51C protein antibody|RAD51L2 antibody|RAD51L2/RAD51C protein antibody|RGD1563765 antibody|Yeast RAD51 homolog 3 antibody
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Uniprot ID
O43502
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Entrez GeneID
5889
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
