Rab3A Antibody

• Catalog number
  PB9322
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Rab3A
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human Rab3A (192-220aa DTADPAVTGAKQGPQLSDQQVPPHQDCAC), different from the related mouse and rat sequences by two amino acids.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Rab3A Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Rab3A Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. This gene is mapped to 19p13.11. Synapsin I stimulated the RAB3A cycle by increasing GTP binding, GTPase activity, and RAB3A recruitment to the synaptic vesicle membrane. Conversely, RAB3A inhibited synapsin I binding to actin and synapsin I-induced synaptic vesicle clustering. It has been found that RAB3A was necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, RAB3A has been found to regulate a late step in synaptic vesicle fusion.
• Related articles
  1. Giovedi, S., Darchen, F., Valtorta, F., Greengard, P., Benfenati, F. Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction. J. Biol. Chem. 279: 43769-43779, 2004. 2. Huang, Y.-Y., Zakharenko, S. S., Schoch, S., Kaeser, P. S., Janz, R., Sudhof, T. C., Siegelbaum, S. A., Kandel, E. R. Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation. Proc. Nat. Acad. Sci. 102: 9365-9370, 2005. 3. Rousseau-Merck M, Zahraoui A, Bernheim A, Touchot N, Miglierina R, Tavitian A et al. (January 1990). "Chromosome mapping of the human ras-related rab3A gene to 19p13.2". Genomics 5 (4): 694–8.
• Gene Name
  RAB3A
• Protein Name
  Ras-related protein Rab-3A
• Gene Full Name
  RAB3A, member RAS oncogene family
• Synonyms
  Rab 3A antibody|RAB 3A member RAS oncogene family antibody|Rab3a antibody|RAB3A member RAS oncogene family antibody|RAB3A_HUMAN antibody|RAS associated protein RAB 3A antibody|RAS associated protein RAB3A antibody|Ras related protein Rab 3A antibody|Ras related protein Rab3A antibody|Ras-related protein Rab-3A antibody
• Uniprot ID
  P20336
• Entrez GeneID
  5864
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Rab3A  
• Gene symbol
  RAB3A, RAB3IL1, RAB3IP
• Short name
  Rab3A Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  RAB3A, member RAS oncogene family (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  RAB3A, member RAS oncogene family, RAB3A and IDBG-37807 and ENSG00000105649 and 5864, ATPase binding, nuclei, Rab3a and IDBG-164008 and ENSMUSG00000031840 and 19339, RAB3A and IDBG-641746 and ENSBTAG00000010635 and 282029

Gene info

• Identity
  HGNC:9777
• Gene
  RAB3A
• Long gene name
  RAB3A, member RAS oncogene family
• Synonyms name
  • RAS-associated protein RAB3A
• Locus
  19p13.11
• Discovery year
  1989-06-30
• Entrez gene record
  5864
• Pubmed identfication
  • 2687157
  • 7532276
• RefSeq identity
  • NM_002866
• Classification
  • RAB, member RAS oncogene GTPases
• VEGA ID
  OTTHUMG00000137378

Gene info

• Identity
  HGNC:9780
• Gene
  RAB3IL1
• Long gene name
  RAB3A interacting protein like 1
• Synonyms gene name
  • RAB3A interacting protein (rabin3)-like 1
• Synonyms
  • GRAB
• Synonyms name
  • guanine nucleotide exchange factor for Rab3A
• GenBank acession
  • AF084557
• Locus
  11q12.2-q12.3
• Discovery year
  1998-07-30
• Entrez gene record
  5866
• Pubmed identfication
  • 11516400
• RefSeq identity
  • NM_013401
• VEGA ID
  OTTHUMG00000167524

Gene info

• Identity
  HGNC:16508
• Gene
  RAB3IP
• Long gene name
  RAB3A interacting protein
• Synonyms
  • RABIN3
  • FLJ22548
  • RABIN8
• Synonyms name
  • rabin3
• Locus
  12q15
• Discovery year
  2001-11-12
• Entrez gene record
  117177
• Pubmed identfication
  • 12221131
• RefSeq identity
  • NM_022456
• VEGA ID
  OTTHUMG00000169437

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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