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Target antigen
PIK3R2
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
rat Theoretical reactivity:human
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human PIK3R2 (427-463aa KYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQL), different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the PIK3R2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The PIK3R2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
PIK3R2 (Phosphatidylinositol 3-kinase, regulatory subunit 2), also called p85-Beta, is an enzyme that in humans is encoded by the PIK3R2 gene. The PIK3R2 gene is mapped on 19p13.11. Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.
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Related articles
1. "Entrez Gene: PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)". 2. Gout I, Dhand R, Panayotou G, Fry MJ, Hiles I, Otsu M, Waterfield MD (Dec 1992). "Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system". The Biochemical Journal. 288 ( Pt 2): 395–405. 3. Volinia S, Patracchini P, Otsu M, Hiles I, Gout I, Calzolari E, Bernardi F, Rooke L, Waterfield MD (Apr 1992). "Chromosomal localization of human p85 alpha, a subunit of phosphatidylinositol 3-kinase, and its homologue p85 beta". Oncogene 7 (4): 789–93.
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Gene Name
PIK3R2
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Protein Name
Phosphatidylinositol 3-kinase regulatory subunit beta
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Gene Full Name
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
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Synonyms
p85 antibody|p85 beta antibody|P85B antibody|P85B_HUMAN antibody|Phosphatidylinositol 3 kinase antibody|Phosphatidylinositol 3 kinase regulatory beta subunit antibody| Phosphatidylinositol 3 kinase regulatory subunit beta antibody|Phosphatidylinositol 3 kinase regulatory subunit polypeptide 2 antibody|Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta) antibody| Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta antibody|Phosphatidylinositol 3-kinase regulatory subunit beta antibody| Phosphoinositide 3 kinase regulatory subunit 2 (beta) antibody|Phosphoinositide 3 kinase regulatory subunit 2 antibody| Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta) antibody|Phosphoinositide 3 kinase regulatory subunit polypeptide 2 antibody| Phosphoinositide 3 kinase, regulatory subunit 2 (beta) antibody|Phosphoinositide 3 kinase, regulatory subunit 2 (p85 beta) antibody|PI3 kinase p85 beta subunit antibody|PI3 kinase p85 subunit beta antibody|PI3-kinase regulatory subunit beta antibody|PI3-kinase subunit p85-beta antibody|PI3K antibody|PI3K regulatory subunit beta antibody|PIK3R 2 antibody|PIK3R2 antibody| PtdIns 3 kinase p85 beta antibody|PtdIns-3-kinase regulatory subunit beta antibody|PtdIns-3-kinase regulatory subunit p85-beta antibody
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Uniprot ID
O00459
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Entrez GeneID
5296
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
