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Target antigen
Livin
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, rat Predicted to work with: mouse
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Analyses
WB,IHC-P
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Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Livin(115-132aa)(a) HTGHQDKVRCFFCYGGLQ), different from the mouse sequence by one amino acid.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Livin Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Livin Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Baculoviral IAP repeat-containing protein 7 is a protein that in humans is encoded by the BIRC7 gene. This protein is a member of the family of inhibitor of apoptosis proteins(IAP) and contains a single copy of a baculovirus IAP repeat(BIR) and a RING finger motif. Its gene is mapped to 20q13.3. It has got 280- and 298- amino acids. The protein is highly expressed in melanomas while lowly expressed in some lymphomas, fetal kidney, fetal liver, testis and thymus. BIRC7 plays a vital role in blocking apoptosis induced.
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Related articles
1. Kasof GM, Gomes BC (May 2001). "Livin, a novel inhibitor of apoptosis protein family member". J Biol Chem 276 (5): 3238–46. 2. Lin JH, Deng G, Huang Q, Morser J (Feb 2001). "KIAP, a novel member of the inhibitor of apoptosis protein family". Biochem Biophys Res Commun 279 (3): 820–31. "Entrez Gene: BIRC7 baculoviral IAP repeat-containing 7 (livin)"
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Gene Name
BIRC7
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Protein Name
Baculoviral IAP repeat-containing protein 7
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Gene Full Name
baculoviral IAP repeat containing 7
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Synonyms
Baculoviral IAP repeat containing 7 antibody|Baculoviral IAP repeat containing protein 7 antibody|Baculoviral IAP repeat-containing protein 7 antibody|BIRC 7 antibody|BIRC7 antibody|BIRC7_HUMAN antibody|KIAP antibody|Kidney inhibitor of apoptosis protein antibody|LIVIN antibody|Livin inhibitor of apotosis antibody|Melanoma inhibitor of apoptosis protein antibody|ML IAP antibody|ML-IAP antibody|MLIAP antibody|RING finger protein 50 antibody|RNF 50 antibody|RNF50 antibody
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Uniprot ID
Q96CA5
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
