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Target antigen
LI Cadherin
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
mouse, rat
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human LI Cadherin(686-699aa LIFEATDDDQHLFR).
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the LI Cadherin Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The LI Cadherin Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Cadherin-17, also known as HPT1 or CDH16 is a protein that in humans is encoded by the CDH17 gene. By somatic cell hybrid analysis and fluorescence in situ hybridization, CDH17 gene is mapped to 8q22.1. This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.
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Related articles
1. Dantzig, A. H., Hoskins, J., Tabas, L. B., Bright, S., Shepard, R. L., Jenkins, I. L., Duckworth, D. C., Sportsman, J. R., Mackensen, D., Rosteck, P. R., Jr., Skatrud, P. L. Association of intestinal peptide transport with a protein related to the cadherin superfamily. cience 264: 430-433, 1994. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.
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Gene Name
CDH17
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Protein Name
Cadherin-17
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Gene Full Name
cadherin 17, LI cadherin(liver-intestine)
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Synonyms
BILL-cadherin antibody|CAD17_HUMAN antibody|Cadherin 16 antibody|Cadherin 17 antibody|Cadherin-17 antibody|CDH16 antibody|CDH17 antibody|FLJ26931 antibody|HPT 1 antibody|human peptide transporter 1 antibody|Intestinal peptide-associated transporter HPT 1 antibody|Intestinal peptide-associated transporter HPT-1 antibody|LI-cadherin antibody|Liver Cadherin antibody|liver intestine cadherin antibody|Liver-intestine cadherin antibody
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Uniprot ID
Q12864
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
