LASP1 Antibody

• Catalog number
  PA1791
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  LASP1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB,IHC-P,ICC
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human LASP1(16-30aa EKVNCLDKFWHKACF), identical to the related rat sequence and different from the related mouse sequence by one amino acid.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the LASP1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The LASP1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  LASP1(LIM and SH3 domain protein 1), also known as LASP1, is a protein that in humans is encoded by the LASP1 gene. This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. LASP1 has been shown to interact with Zyxin. Tomasetto et al.(1995) mapped the LASP1 gene to chromosome 17q11-q21.3 by radioactive in situ hybridization. Northern blot analysis revealed that LASP1 mRNA was expressed at a basal level in all normal tissues examined and overexpressed in 8% of primary breast cancers. In most of these cancers, LASP1 and ERBB2 were simultaneously overexpressed.
• Related articles
  1. Schreiber, V., Masson, R., Linares, J. L., Mattei, M. G., Tomasetto, C., Rio, M. C.Chromosomal assignment and expression pattern of the murine Lasp-1 gene.Gene 207: 171-175, 1998. 2. Tomasetto, C., Moog-Lutz, C., Regnier, C. H., Schreiber, V., Basset, P., Rio, M.-C.Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains.FEBS Lett. 373: 245-249, 1995. 3. Tomasetto, C., Regnier, C., Moog-Lutz, C., Mattei, M. G., Chenard, M. P., Lidereau, R., Basset, P., Rio, M. C.Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17.Genomics 28: 367-376, 1995.
• Gene Name
  LASP1
• Protein Name
  LIM and SH3 domain protein 1(LASP-1)
• Gene Full Name
  LIM and SH3 protein 1
• Synonyms
  LASP 1 antibody|LASP-1 antibody|LASP1 antibody|LASP1_HUMAN antibody|LIM and SH3 domain protein 1 antibody|LIM and SH3 protein 1 antibody|Metastatic lymph node gene 50 protein antibody|MLN 50 antibody|MLN50 antibody|OTTHUMP00000164238 antibody|OTTHUMP00000164239 antibody
• Uniprot ID
  Q14847
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LASP1  
• Gene symbol
  LASP1
• Short name
  LASP1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  LASP1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6513
• Gene
  LASP1
• Long gene name
  LIM and SH3 protein 1
• Synonyms
  • MLN50
  • Lasp-1
• Locus
  17q12
• Discovery year
  1997-05-22
• Entrez gene record
  3927
• Pubmed identfication
  • 7490069
  • 25622104
• RefSeq identity
  • NM_006148
• Classification
  • LIM domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133182

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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