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Target antigen
HDJ2
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human HDJ2(369-384aa NQERRRHYNGEAYEDD), identical to the related rat and mouse sequences.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the HDJ2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The HDJ2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
DNAJA1(DnaJ homolog subfamily A member 1), also called DJA1, HSDJ, HSPF4, is a protein that in humans is encoded by the DNAJA1 gene. The deduced 397-amino acid DNAJA1 protein is 32% identical to E. coli DnaJ, with the highest identity in the N-terminal region. Among the known DNAJ homologs in S. cerevisiae, DNAJA1 is most identical to YDJ1, which may be involved in the transport of certain proteins into the mitochondria and endoplasmic reticulum. Dja1 is expressed in mouse testis and prostate by immunohistochemical analysis and Western blot analysis. Transplantation experiments with fluorescence-tagged spermatogonia into Dja1 -/- mice revealed a primary defect of Sertoli cells in maintaining spermiogenesis at steps 8 and 9.
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Related articles
1. Chellaiah, A., Davis, A., Mohanakumar, T. Cloning of a unique human homologue of the Escherichia coli DNAJ heat shock protein. Biochim. Biophys. Acta 1174: 111-113, 1993. 2. Banasavadi-Siddegowda YK et al. FKBP38 Peptidylprolyl Isomerase Promotes the Folding of Cystic Fibrosis Transmembrane Conductance Regulator in the Endoplasmic Reticulum. J Biol Chem 286:43071-80 (2011). 3. Chellaiah A, Davis A, Mohanakumar T (Aug 1993). "Cloning of a unique human homologue of the Escherichia coli DNAJ heat shock protein". Biochim Biophys Acta 1174 (1): 111–3.
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Gene Name
DNAJA1
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Protein Name
DnaJ homolog subfamily A member 1
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Gene Full Name
DnaJ(Hsp40) homolog, subfamily A, member 1
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Synonyms
DJ 2 antibody|DJ2 antibody|DjA1 antibody|DnaJ(Hsp40) homolog, subfamily A, member 1 antibody|DnaJ homolog subfamily A member 1 antibody|DnaJ protein homolog 2 antibody|DNAJ2 antibody|Dnaja1 antibody|DNJA1_HUMAN antibody|hDJ 2 antibody|HDJ-2 antibody|HDJ2 antibody|Heat shock 40 kDa protein 4 antibody|heat shock protein DNAJ like 2 antibody|Heat shock protein J2 antibody|HSDJ antibody|HSJ-2 antibody|HSJ2 antibody|HSPF4 antibody|Human DnaJ protein 2 antibody|NEDD7 antibody|Neural precursor cell expressed developmentally down regulated 7 antibody|OTTHUMP00000021193 antibody
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Uniprot ID
P31689
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps