HDAC11 Antibody

• Catalog number
  PB9630
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  HDAC11
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11 (47-81aa NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN), different from the related mouse sequence by one amino acid.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the HDAC11 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The HDAC11 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Histone deacetylase 11 is a 39kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.
• Related articles
  1. "Entrez Gene: HDAC11 histone deacetylase 11". 2. Gao L, Cueto MA, Asselbergs F, Atadja P (Jul 2002). "Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family".The Journal of Biological Chemistry 277(28): 25748–55.
• Gene Name
  HDAC11
• Protein Name
  Histone deacetylase 11
• Gene Full Name
  histone deacetylase 11
• Synonyms
  FLJ22237 antibody|HD 11 antibody|HD11 antibody|HDA11_HUMAN antibody|HDAC 11 antibody|HDAC11 antibody|Histone deacetylase 11 antibody
• Uniprot ID
  Q96DB2
• Entrez GeneID
  79885
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HDAC11  
• Gene symbol
  HDAC11, HDAC11-AS1
• Short name
  HDAC11 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  HDAC11 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19086
• Gene
  HDAC11
• Long gene name
  histone deacetylase 11
• GenBank acession
  • AK025426
• Locus
  3p25.1
• Discovery year
  2002-08-09
• Entrez gene record
  79885
• Pubmed identfication
  • 11948178
• RefSeq identity
  • NM_024827
• Classification
  • Histone deacetylases, class IV
• VEGA ID
  OTTHUMG00000129800

Gene info

• Identity
  HGNC:40868
• Gene
  HDAC11-AS1
• Long gene name
  HDAC11 antisense RNA 1
• Synonyms gene name
  • HDAC11 antisense RNA 1 (non-protein coding)
• Locus
  3p25.1
• Discovery year
  2011-07-28
• Entrez gene record
  100874101
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000155438

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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