-
Target antigen
FbxL4
-
Clonality
Polyclonal antibody
-
Clone
Polyclonal antibody
-
Raised in
rabbit
-
Type of the antibody
IgG polyclonal antibody
-
Product form
freeze-dried
-
Reacts with species
human, mouse, rat
-
Analyses
WB,IHC-P
-
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human FbxL4(552-565aa DELASNCTRLQQLD), different from the related mouse and rat sequences by one amino acid.
-
Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
-
Purification
Immunogen affinity purified.
-
Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
-
Storage condtions
Keep the FbxL4 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
-
Tips
The FbxL4 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
-
Background
FBXL4, also known as FBL4 or FBL5 encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. This gene is mapped to 6q16.1. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A.
-
Related articles
1. Ilyin, G. P., Rialland, M., Pigeon, C., Guguen-Guillouzo, C. cDNA cloning and expression analysis of new members of the mammalian F-box protein family. Genomics 67: 40-47, 2000. 2. Jin, J., Cardozo, T., Lovering, R. C., Elledge, S. J., Pagano, M., Harper, J. W. Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev. 18: 2573-2580, 2004.
-
Gene Name
FBXL4
-
Protein Name
F-box/LRR-repeat protein 4
-
Gene Full Name
F-box and leucine-rich repeat protein 4
-
Synonyms
F box and leucine rich repeat protein 4 antibody|F box protein FBL4/FBL5 antibody|F box/LRR repeat protein 4 antibody|F-box and leucine-rich repeat protein 4 antibody|F-box protein FBL 4 antibody|F-box protein FBL4/FBL5 antibody|F-box/LRR-repeat protein 4 antibody|FBL 4 antibody|FBL 5 antibody|FBL4 antibody|FBL5 antibody|Fbxl4 antibody|FBXL4_HUMAN antibody
-
Uniprot ID
Q9UKA2
-
Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
