Cystatin A Antibody

• Catalog number
  PA2105
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Cystatin A
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  mouse, rat
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human Cystatin A(77-90aa NEDLVLTGYQVDKN).
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Cystatin A Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Cystatin A Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Cystatin A also called Stefin A is a protein that in humans is encoded by the CSTA gene. Cystatin A is a cysteine proteinase inhibitor that belongs to family 1 of the cystatin superpamily. This gene was assigned to human chromosome 3q21.1. This is an intracellular thiol proteinase inhibitor. Cystatin A plays an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. Stefins have been proposed as prognostic and diagnostic tools for cancer.
• Related articles
  1. Blaydon, D. C., Nitoiu, D., Eckl, K.-M., Cabral, R. M., Bland, P., Hausser, I., van Heel, D. A., Rajpopat, S., Fischer, J., Oji, V., Zvulunov, A., Traupe, H., Hennies, H. C., Kelsell, D. P. Mutations in CSTA, encoding cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion. Am. J. Hum. Genet. 89: 564-571, 2011. 2. Samuelsson, L., Stiller, C., Friberg, C., Nilsson, C., Inerot, A., Wahlstrom, J.Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5. J. Invest. Derm. 122: 1399-1400, 2004. 3. Vasilopoulos, Y., Walters, J., Cork, M. J., Duff, G. W., Sagoo, G. S., Tazi-Ahnini, R.Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5.Europ. J. Hum. Genet. 16: 1002-1009, 2008.
• Gene Name
  CSTA
• Protein Name
  Cystatin-A
• Gene Full Name
  cystatin A(stefin A)
• Synonyms
  AREI antibody|CSTA antibody|CSTA protein antibody|Cystatin A antibody|Cystatin AS antibody|Cystatin-A antibody|Cystatin-AS antibody|CystatinA antibody|CYTA_HUMAN antibody|Stefin A antibody|Stefin A1 antibody|Stefin-A antibody|StefinA antibody|STF 1 antibody|STF1 antibody|STFA antibody
• Uniprot ID
  P01040
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cystatin  
• Gene symbol
  CSTA
• Short name
  Cystatin A Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Cystatin A (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2481
• Gene
  CSTA
• Long gene name
  cystatin A
• Synonyms gene
  • STF1
  • STFA
• Synonyms gene name
  • cystatin A (stefin A)
• Synonyms name
  • stefin A
• Locus
  3q21.1
• Discovery year
  1990-02-06
• Entrez gene record
  1475
• Pubmed identfication
  • 1674139
• RefSeq identity
  • NM_005213
• Classification
  • Cystatins, type 1
• VEGA ID
  OTTHUMG00000159488

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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