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Target antigen
Cdk9
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, mouse
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Analyses
WB,IHC-P
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Immunogen
E.coli-derived human Cdk9 recombinant protein (Position: H141-F372). Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse and rat Cdk9.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Cdk9 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Cdk9 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
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Related articles
1. "Entrez Gene: CDK9 cyclin-dependent kinase 9 (CDC2-related kinase)". 2. MacLachlan TK, Sang N, De Luca A, Puri PL, Levrero M, Giordano A (1998). "Binding of CDK9 to TRAF2". J. Cell. Biochem. 71 (4): 467–78.
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Gene Name
CDK9
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Protein Name
Cyclin-dependent kinase 9
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Gene Full Name
cyclin-dependent kinase 9
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Synonyms
C 2k antibody|C-2K antibody|CDC2 related kinase antibody|CDC2L4 antibody|Cdk 9 antibody| Cdk9 antibody|CDK9_HUMAN antibody|Cell division cycle 2 like protein kinase 4 antibody|Cell division cycle 2-like protein kinase 4 antibody|Cell division protein kinase 9 antibody| CTK1 antibody|Cyclin dependent kinase 9 antibody|Cyclin-dependent kinase 9 antibody|PITALRE antibody|Serine threonine protein kinase PITALRE antibody|Serine/threonine-protein kinase PITALRE antibody|TAK antibody|Tat associated kinase complex catalytic subunit antibody
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Uniprot ID
P50750
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Entrez GeneID
1025
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
