CD47 Antibody
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Catalog numberPA2223
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PricePlease ask
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Size0,1 mg
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Target antigenCD47
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman
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AnalysesWB,IHC-P
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ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human CD47(308-323aa EPLNAFKESKGMMNDE), identical to the related rat sequence.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the CD47 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe CD47 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundCD47, also known as IAP or MER6, is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 gene belongs to the immunoglobulin superfamily. This gene is mapped to 3q13.12. CD47 gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
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Related articles1. Bras, M., Yuste, V. J., Roue, G., Barbier, S., Sancho, P., Virely, C., Rubio, M., Baudet, S., Esquerda, J. E., Merle-Beral, H., Sarfati, M., Susin, S. A. Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. Molec. Cell. Biol. 27: 7073-7088, 2007. 2. Han, X., Sterling, H., Chen, Y., Saginario, C., Brown, E. J., Frazier, W. A., Lindberg, F. P., Vignery, A. CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleation. J. Biol. Chem. 275: 37984-37992, 2000. 3. Oldenborg, P.-A., Zheleznyak, A., Fang, Y.-F., Lagenaur, C. F., Gresham, H. D., Lindberg, F. P. Role of CD47 as a marker of self on red blood cells. Science 288: 2051-2054, 2000.
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Gene NameCD47
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Protein NameLeukocyte surface antigen CD47
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Gene Full NameCD47 molecule
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SynonymsAntigenic surface determinant protein OA3 antibody|CD 47 antibody|CD47 antibody|Cd47 antibody|CD47 antigen(Rh-related antigen, integrin-associated signal transducer) antibody|CD47 antigen antibody|CD47 glycoprotein antibody|CD47 molecule antibody|CD47_HUMAN antibody|IAP antibody|Integrin Associated Protein antibody|Integrin associated signal transducer antibody|Integrin-associated protein antibody|Leukocyte surface antigen CD47 antibody|MER 6 antibody|MER6 antibody|OA 3 antibody|OA3 antibody|OTTHUMP00000041152 antibody|OTTHUMP00000041153 antibody|Protein MER6 antibody|Rh related antigen antibody
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Uniprot IDQ08722
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCD47
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Short nameCD47 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameCD47 molecule (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetCD47 molecule, IAP and MER6 and OA3, CD47 and IDBG-48744 and ENSG00000196776 and 961, thrombospondin receptor activity, Plasma membranes, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661
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Gene info
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Identity
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Gene
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Long gene nameCD47 molecule
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Synonyms gene
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Synonyms gene name
- CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-12-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Ig-like cell adhesion molecule family
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
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Tree numbers
- E01.370.225.500.195.107.595.500.150
- E01.370.225.625.107.595.500.150
- E05.200.500.195.107.595.500.150
- E05.200.625.107.595.500.150
- E05.242.195.107.595.500.150
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data