CARD4 Antibody

• Catalog number
  PB9294
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  CARD4
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB,IHC-P
• Immunogen
  E.coli-derived human CARD4 recombinant protein (Position: M1-M160). Human CARD4 shares 82% amino acid (aa) sequence identity with mouse CARD4.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the CARD4 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The CARD4 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is mapped to 7p14.3. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains a caspase recruitment domain (CARD). This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. What wore, it has been shown that NOD1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.
• Related articles
  1. Chamaillard, M., Hashimoto, M., Horie, Y., Masumoto, J., Su, Q., Saab, L., Ogura, Y., Kawasaki, A., Fukase, K., Kusumoto, S., Valvano, M. A., Foster, S. J., Mak, T. W., Nunez, G., Inohara, N. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nature Immun. 4: 702-707, 2003. 2. da Silva Correia, J., Miranda, Y., Austin-Brown, N., Hsu, J., Mathison, J., Xiang, R., Zhou, H., Li, Q., Han, J., Ulevitch, R. J. Nod1-dependent control of tumor growth. Proc. Nat. Acad. Sci. 103: 1840-1845, 2006. 3. Martinon F, Tschopp J (2006). "NLRs join TLRs as innate sensors of pathogens.".Trends Immunol. 26 (8): 447–54.
• Gene Name
  NOD1
• Protein Name
  Nucleotide-binding oligomerization domain-containing protein 1
• Gene Full Name
  nucleotide-binding oligomerization domain containing 1
• Synonyms
  CARD 4 antibody|CARD4 antibody|Caspase recruitment domain 4 antibody|Caspase recruitment domain containing protein 4 antibody|Caspase recruitment domain family member 4 antibody|Caspase recruitment domain protein 4 antibody|Caspase recruitment domain-containing protein 4 antibody|CLR 7.1 antibody|CLR7.1 antibody|NLR family CARD domain containing 1 antibody|NLRC 1 antibody|NLRC1 antibody|NOD 1 antibody|Nod1 antibody|NOD1 protein antibody|NOD1_HUMAN antibody|Nucleotide binding oligomerization domain containing 1 antibody|Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1 antibody|Nucleotide-binding oligomerization domain-containing protein 1 antibody|Protein Nod1 antibody
• Uniprot ID
  Q9Y239
• Entrez GeneID
  10392
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CARD4  
• Gene symbol
  NOD1
• Short name
  CARD4 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  CARD4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16390
• Gene
  NOD1
• Long gene name
  nucleotide binding oligomerization domain containing 1
• Synonyms gene
  • CARD4
• Synonyms gene name
  • caspase recruitment domain family, member 4
• Synonyms
  • NLRC1
  • CLR7.1
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
  • NLR family, CARD domain containing 1
• GenBank acession
  • AF126484
• Locus
  7p14.3
• Discovery year
  2001-12-11
• Entrez gene record
  10392
• Pubmed identfication
  • 10224040
  • 10329646
• Classification
  • NLR family
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000023923

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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