Target antigen
Calcineurin alpha
Clonality
Monoclonal antibody
Clone
CN-A1
Raised in
mice
Type of the antibody
IgG1 monoclonal antibody
Product form
solution
Reacts with species
Human, bovine, rat
Analyses
WB,IHC-P
Immunogen
Bovine brain calcineurin.
Product configuration
Each vial contains 50% glycerol, 1.2% Na acetate, 1% BSA, 0.02% NaN3.
Purification
Ascites
Solubilization
Solution
Storage condtions
Keep the Calcineurin alpha Antibody ( CNA1)at minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
Tips
The Calcineurin alpha Antibody ( CNA1) did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
Background
Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha(PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase(calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast.
Related articles
1. Giri, P.; Higuchi, S.; Kincaid, R. L. : Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Biochem. Biophys. Res. Commun. 181: 252-258, 1991. 2. Sun, L.; Blair, H. C.; Peng, Y.; Zaidi, N.; Adebanjo, O. A.; Wu, X. B.; Wu, X. Y.; Iqbal, J.; Epstein, S.; Abe, E.; Moonga, B. S.; Zaidi, M. : Calcineurin regulates bone formation by the osteoblast. Proc. Nat. Acad. Sci. 102: 17130-17135, 2005. 3. Wang, M. G.; Yi, H.; Guerini, D.; Klee, C. B.; McBride, O. W. : Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-q22 and 2p16-p15 respectively. Cytogenet. Cell Genet. 72: 236-241, 1996.
Gene Name
PPP3R1
Protein Name
Calcineurin subunit B type 1
Gene Full Name
protein phosphatase 3, regulatory subunit B, alpha
Synonyms
CNA2|CNB|CNB1|CALNB1|Protein phosphatase 2B regulatory subunit 1|Protein phosphatase 3 regulatory subunit B alpha isoform 1
Uniprot ID
Human(P63098), Mouse(Q63810), Rat(P63100)
Entrez GeneID
Human(5534), Mouse(19058), Rat(29748)
Description
The Calcineurin alpha Antibody ( CNA1) is a α- or alpha protein sometimes glycoprotein present in blood.
Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps
